Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments
about
Structure- and substrate-based inhibitor design for Clostridium botulinum neurotoxin serotype ASingle-molecule studies of the neuronal SNARE fusion machinery.Basic tetrapeptides as potent intracellular inhibitors of type A botulinum neurotoxin protease activity.A yeast assay probes the interaction between botulinum neurotoxin serotype B and its SNARE substrate.SNARE zippering and synaptic strength.The zinc-dependent protease activity of the botulinum neurotoxinsReduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: evidence for an exocytotic mechanism.Monoclonal Antibodies that Inhibit the Proteolytic Activity of Botulinum Neurotoxin Serotype/B.Inhibition of catalytic activities of botulinum neurotoxin light chains of serotypes A, B and E by acetate, sulfate and calcium.Clinical uses of botulinum neurotoxins: current indications, limitations and future developmentsUse of a recombinant fluorescent substrate with cleavage sites for all botulinum neurotoxins in high-throughput screening of natural product extracts for inhibitors of serotypes A, B, and E.The C terminus of the catalytic domain of type A botulinum neurotoxin may facilitate product release from the active siteReceptor and substrate interactions of clostridial neurotoxins.Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells.Targeted secretion inhibitors-innovative protein therapeuticsClostridial neurotoxins: mechanism of SNARE cleavage and outlook on potential substrate specificity reengineering.The blockade of the neurotransmitter release apparatus by botulinum neurotoxins.Synaptic vesicle chips to assay botulinum neurotoxins.Fluorigenic substrates for the protease activities of botulinum neurotoxins, serotypes A, B, and F.Development of novel assays for botulinum type A and B neurotoxins based on their endopeptidase activities.Substrate recognition mechanism of VAMP/synaptobrevin-cleaving clostridial neurotoxins.Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin.Tyrosine phosphorylation of botulinum neurotoxin protease domainsInsights into the different catalytic activities of Clostridium neurotoxinsMetal substitution of tetanus neurotoxin.A high-affinity competitive inhibitor of type A botulinum neurotoxin protease activity.Design and synthesis of substrate-based inhibitors of botulinum neurotoxin type B metalloprotease.Toxicity of botulinum toxin type B (BoNT/B)BoNT/B LC cleaves target cell VAMP2TeNT LC cleaves target cell VAMP2Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis.
P2860
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P2860
Differences in the protease activities of tetanus and botulinum B toxins revealed by the cleavage of vesicle-associated membrane protein and various sized fragments
description
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Dezember 1994 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/12/27)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/12/27)
@nl
наукова стаття, опублікована в грудні 1994
@uk
مقالة علمية (نشرت في 27-12-1994)
@ar
name
Differences in the protease ac ...... in and various sized fragments
@ast
Differences in the protease ac ...... in and various sized fragments
@en
Differences in the protease ac ...... in and various sized fragments
@nl
type
label
Differences in the protease ac ...... in and various sized fragments
@ast
Differences in the protease ac ...... in and various sized fragments
@en
Differences in the protease ac ...... in and various sized fragments
@nl
prefLabel
Differences in the protease ac ...... in and various sized fragments
@ast
Differences in the protease ac ...... in and various sized fragments
@en
Differences in the protease ac ...... in and various sized fragments
@nl
P2093
P356
P1433
P1476
Differences in the protease ac ...... in and various sized fragments
@en
P2093
C. C. Shone
J. O. Dolly
P304
15365–15374
P356
10.1021/BI00255A017
P407
P577
1994-12-27T00:00:00Z