NMR analyses of the Gbetagamma binding and conformational rearrangements of the cytoplasmic pore of G protein-activated inwardly rectifying potassium channel 1 (GIRK1).
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Kir3 channel signaling complexes: focus on opioid receptor signalingCrystal Structure of the Mammalian GIRK2 K+ Channel and Gating Regulation by G Proteins, PIP2, and SodiumX-ray structure of the mammalian GIRK2–βγ G-protein complexQuantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.GPCR mediated regulation of synaptic transmission.Structural basis for modulation of gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by i/o-family G protein α subunit (Gαi/o).Atypical membrane-embedded phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2)-binding site on p47(phox) Phox homology (PX) domain revealed by NMR.A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).Conformational dynamics of Kir3.1/Kir3.2 channel activation via δ-opioid receptors.Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels.Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipidsConformational changes underlying pore dilation in the cytoplasmic domain of mammalian inward rectifier K+ channels.Secondary anionic phospholipid binding site and gating mechanism in Kir2.1 inward rectifier channels.New insights into the therapeutic potential of Girk channels.Cross-saturation and transferred cross-saturation experiments.A computational model predicts that Gβγ acts at a cleft between channel subunits to activate GIRK1 channels.Recruitment of Gβγ controls the basal activity of G-protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1.Nuclear Magnetic Resonance Approaches for Characterizing Protein-Protein Interactions.Structural basis of efficient electron transport between photosynthetic membrane proteins and plastocyanin in spinach revealed using nuclear magnetic resonance.Structural basis for the ethanol action on G-protein-activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy.
P2860
Q27006957-C5720533-E0EE-4429-B39D-353F02DA2F63Q27674638-A2652EDD-D640-48EC-85B7-17626B48FC22Q27678502-7CA05E28-A12B-46DD-A855-A65A216ADDAAQ34055491-83998060-1142-49EC-86F3-AEAA0ACBD46CQ35870239-8A55C301-7EC1-4874-8B92-9B99061A983BQ36003866-082455AA-F791-4446-972D-E8E918B579C0Q36006972-3E55D7E7-B5BB-4AE9-B535-983CD03B0D29Q36257591-B7FF304D-DFDD-433F-A450-A9A4C88A49EFQ36418792-2FF27F63-E3A0-4B5E-9F80-628D7FB3613CQ36573185-2D6F79E6-680F-4687-8470-0077A914D1BBQ36900728-B8AF3879-04B5-4E16-946B-B7F5E4EB98EEQ37216161-FE7697A1-5590-4A88-8763-F7E976A3E3B5Q37296710-8EAE3A4D-6BFF-46FC-8050-A63A3770F8DEQ37403781-DEFD97A6-8F22-403B-B860-E6B5540DC0D8Q38165545-663E06A3-BC50-4A1D-9F2B-BC89E7A41A68Q38208097-C2EE5E20-DC74-4285-94B7-3418AF357848Q42097716-ED24D651-1DFB-421B-8CC6-5D4F51B23BB3Q42468291-2B7CE92D-BD07-48D2-B664-9FDCFC47611BQ47617927-9CE2729D-8827-400D-9FEE-A9904ACCB85EQ48045708-48CC7D8F-3A5F-487D-A852-13AD103DD1CCQ53834764-D3CC4A66-80A0-4BB4-84DC-134D642063D5
P2860
NMR analyses of the Gbetagamma binding and conformational rearrangements of the cytoplasmic pore of G protein-activated inwardly rectifying potassium channel 1 (GIRK1).
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@ast
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@en
NMR analyses of the Gbetagamma ...... rectifying potassium channel 1
@nl
type
label
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@ast
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@en
NMR analyses of the Gbetagamma ...... rectifying potassium channel 1
@nl
prefLabel
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@ast
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@en
NMR analyses of the Gbetagamma ...... rectifying potassium channel 1
@nl
P2093
P2860
P356
P1476
NMR analyses of the Gbetagamma ...... g potassium channel 1 (GIRK1).
@en
P2093
Ichio Shimada
Koh Takeuchi
Mariko Yokogawa
Masanori Osawa
P2860
P304
P356
10.1074/JBC.M110.160754
P407
P577
2010-11-12T00:00:00Z