Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family
about
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.Diadenosine tetraphosphate hydrolase is part of the transcriptional regulation network in immunologically activated mast cellsTranscription factor MITF regulates cardiac growth and hypertrophyMLANA/MART1 and SILV/PMEL17/GP100 are transcriptionally regulated by MITF in melanocytes and melanomaSumoylation of MITF and its related family members TFE3 and TFEBA new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factorThe regulation of cathepsin K gene expressionVMD2 promoter requires two proximal E-box sites for its activity in vivo and is regulated by the MITF-TFE familyThe expression of Clcn7 and Ostm1 in osteoclasts is coregulated by microphthalmia transcription factorStrawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMPThe transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.Hexane-Soluble Fraction of the Common Fig, Ficus carica, Inhibits Osteoclast Differentiation in Murine Bone Marrow-Derived Macrophages and RAW 264.7 Cells.Molecular stress-inducing compounds increase osteoclast formation in a heat shock factor 1 protein-dependent mannerC-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3.Mitf induction by RANKL is critical for osteoclastogenesis.A novel isoform of microphthalmia-associated transcription factor inhibits IL-8 gene expression in human cervical stromal cellsThe study of mechanisms of protective effect of Rg1 against arthritis by inhibiting osteoclast differentiation and maturation in CIA miceSumoylation modulates transcriptional activity of MITF in a promoter-specific mannerNovel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescenceInterallelic complementation at the mouse Mitf locus.The basic helix-loop-helix leucine zipper transcription factor Mitf is conserved in Drosophila and functions in eye development.A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression.Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaBInhibition of osteoclast differentiation and bone resorption by N-methylpyrrolidoneThe genetic basis for skeletal diseases.Activation of liver X receptor (LXR) inhibits receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast differentiation in an LXRβ-dependent mechanismDeletion of histone deacetylase 7 in osteoclasts decreases bone mass in mice by interactions with MITF.Toddaculin, Isolated from of Toddalia asiatica (L.) Lam., Inhibited Osteoclastogenesis in RAW 264 Cells and Enhanced Osteoblastogenesis in MC3T3-E1 CellsThe 19S proteasomal lid subunit POH1 enhances the transcriptional activation by Mitf in osteoclasts.Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiationWhen developmental biology meets human pathologyMolecular genetics and cellular features of TFE3 and TFEB fusion kidney cancersThe endocytic pathway in microglia during health, aging and Alzheimer's disease.PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.Transcription Factor Tfe3 Directly Regulates Pgc-1alpha in MuscleAtypical CTSK transcripts and ARNT transcription read-through into CTSK.The role played by key transcription factors in activated mast cells.A RANKL-PKCβ-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts.Aspirin inhibits osteoclastogenesis by suppressing the activation of NF-κB and MAPKs in RANKL-induced RAW264.7 cells
P2860
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P2860
Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family
description
2001 nî lūn-bûn
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2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Linking osteopetrosis and pycn ...... ia transcription factor family
@ast
Linking osteopetrosis and pycn ...... ia transcription factor family
@en
Linking osteopetrosis and pycn ...... ia transcription factor family
@nl
type
label
Linking osteopetrosis and pycn ...... ia transcription factor family
@ast
Linking osteopetrosis and pycn ...... ia transcription factor family
@en
Linking osteopetrosis and pycn ...... ia transcription factor family
@nl
prefLabel
Linking osteopetrosis and pycn ...... ia transcription factor family
@ast
Linking osteopetrosis and pycn ...... ia transcription factor family
@en
Linking osteopetrosis and pycn ...... ia transcription factor family
@nl
P2093
P2860
P356
P1476
Linking osteopetrosis and pycn ...... ia transcription factor family
@en
P2093
Horstmann M
Motyckova G
Weilbaecher KN
P2860
P304
P356
10.1073/PNAS.091479298
P407
P577
2001-05-01T00:00:00Z