Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB - Wikidata - awgldk - TriplyDB

Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB

Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB

http://www.wikidata.org/entity/Q35084886

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Giant cell tumor of the temporal bone--a case report Giant cell tumour of bone: morphological, biological and histogenetical aspects The clinical approach toward giant cell tumor of bone Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice Molecular biology and therapeutics in musculoskeletal oncology.The epidemiology of malignant giant cell tumors of bone: an analysis of data from the Surveillance, Epidemiology and End Results Program (1975-2004).Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer.Osteonecrosis of the jaw in a patient on Denosumab.Collagenase expression and activity in the stromal cells from giant cell tumour of bone.Giant cell tumor in a case of Paget's disease of bone: an aggressive benign tumor exhibiting a quick response to an innovative therapeutic agent.Targeting the giant cell tumor stromal cell: functional characterization and a novel therapeutic strategy Giant cell tumour of bone: new treatments in development.Surgical downstaging in an open-label phase II trial of denosumab in patients with giant cell tumor of bone.Modern interpretation of giant cell tumor of bone: predominantly osteoclastogenic stromal tumor.Rank ligand as a target in musculoskeletal neoplasms.Phenotypic and molecular differences between giant-cell tumour of soft tissue and its bone counterpart.Histogenetic characterization of giant cell tumor of bone A case of thoracic giant cell tumor of bone and discussion of radiological features and current management practices.Retrospective analysis of patients with rare-site and metastatic giant cell tumor.Immune response to RB1-regulated senescence limits radiation-induced osteosarcoma formation.Clinical applications of RANK-ligand inhibition.Denosumab treatment of inoperable or locally advanced giant cell tumor of bone.Targeted therapies: the rare cancer paradigm.Therapeutic targeting of osteoclast function and pathways.The multidisciplinary management of giant cell tumor of bone.Giant cell tumor of bone: current treatment options.Giant cell tumor of bone: a neoplasm or a reactive condition?Neoadjuvant denosumab for extensive giant cell tumor in os ischium: a case report.Overexpression of hypoxia-inducible factor-1α and vascular endothelial growth factor in sacral giant cell tumors and the correlation with tumor microvessel density A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases Giant cell tumor of bone in childhood: clinical aspects and novel therapeutic targets.Giant cell tumor: rapid recurrence after cessation of long-term denosumab therapy.Post-surgery fluids promote transition of cancer stem cell-to-endothelial and AKT/mTOR activity, contributing to relapse of giant cell tumors of bone.Raloxifene can reduce giant cell tumor recurrence: a new adjuvant therapy.Identification of new genes associated to senescent and tumorigenic phenotypes in mesenchymal stem cells.Gene expression profiling of giant cell tumor of bone reveals downregulation of extracellular matrix components decorin and lumican associated with lung metastasis.In Vitro Study of the Effects of Denosumab on Giant Cell Tumor of Bone: Comparison with Zoledronic Acid.Clinicopathological Features of a Series of 27 Cases of Post-Denosumab Treated Giant Cell Tumors of Bones: A Single Institutional Experience at a Tertiary Cancer Referral Centre, India.Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.[Sarcoma gene signatures].

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P2860

Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB

http://www.wikidata.org/entity/Q35084886

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Molecular profiling of giant c ...... vator of nuclear factor kappaB

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Molecular profiling of giant c ...... vator of nuclear factor kappaB

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Molecular profiling of giant c ...... vator of nuclear factor kappaB

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Molecular profiling of giant c ...... vator of nuclear factor kappaB

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The American Journal of Pathology

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Molecular profiling of giant c ...... vator of nuclear factor kappaB

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P2093

Andrew J Holloway

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David M Thomas

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Gerald J Atkins

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Gerald Powell

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Ian Dickinson

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John L Slavin

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Maya Kansara

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Melanie K Trivett

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Paul Simmons

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Peter F M Choong

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P2860

Human giant cell tumors of bone identification and characterization of cell types

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.

Gene expression of osteoprotegerin ligand, osteoprotegerin, and receptor activator of NF-kappaB in giant cell tumor of bone: possible involvement in tumor cell-induced osteoclast-like cell formation

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Bone loss. Factors that regulate osteoclast differentiation: an update.

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

Identification of a novel 135-kDa Grb2-binding protein in osteoclasts

Osteoclast inhibitory lectin, a family of new osteoclast inhibitors

The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice

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