Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration. - Wikidata - awgldk - TriplyDB

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.

http://www.wikidata.org/entity/Q34518577

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Alzheimer mechanisms and therapeutic strategies Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin Synapses and Alzheimer's disease Amyloid-β-Induced Dysregulation of AMPA Receptor Trafficking New Features about Tau Function and Dysfunction Dysfunction of NMDA receptors in Alzheimer's disease Tau: The Center of a Signaling Nexus in Alzheimer's Disease Nuclear Tau and Its Potential Role in Alzheimer's Disease Tau Oligomers: The Toxic Player at Synapses in Alzheimer's Disease Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia Mouse models of frontotemporal dementia Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease Breaking the Code of Amyloid-β Oligomers Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing Problem Common transcriptional signatures in brain tissue from patients with HIV-associated neurocognitive disorders, Alzheimer's disease, and Multiple Sclerosis Alzheimer's disease--a panorama glimpse Molecular mechanisms of dendrite stability Synaptic dysfunction and septin protein family members in neurodegenerative diseases Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?Tau Protein Mediates APP Intracellular Domain (AICD)-Induced Alzheimer's-Like Pathological Features in Mice The dendritic hypothesis for Alzheimer's disease pathophysiology.Spines, plasticity, and cognition in Alzheimer's model mice Tau physiology and pathomechanisms in frontotemporal lobar degeneration Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss Genotype-specific differences between mouse CNS stem cell lines expressing frontotemporal dementia mutant or wild type human tau Brain intraventricular injection of amyloid-β in zebrafish embryo impairs cognition and increases tau phosphorylation, effects reversed by lithium Synaptic protein α1-takusan mitigates amyloid-β-induced synaptic loss via interaction with tau and postsynaptic density-95 at postsynaptic sites Microtubule-associated protein tau is essential for long-term depression in the hippocampus Tau-mediated synaptic damage in Alzheimer's disease Unexpected gain of function for the scaffolding protein plectin due to mislocalization in pancreatic cancer.Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice.Electrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathy Brain amyloid-β oligomers in ageing and Alzheimer's disease.Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn.Preventive methylene blue treatment preserves cognition in mice expressing full-length pro-aggregant human Tau.Tau protein is essential for stress-induced brain pathology

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P2860

Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration.

http://www.wikidata.org/entity/Q34518577

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@ast

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@en

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@nl

type

label

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@ast

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@en

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@nl

prefLabel

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@ast

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@en

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@nl

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P356

J.NEURON.2010.11.030

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P1476

Tau mislocalization to dendrit ...... endently of neurodegeneration.

@en

P2093

Brian R Hoover

http://www.w3.org/2001/XMLSchema#string

Dezhi Liao

http://www.w3.org/2001/XMLSchema#string

George A Carlson

http://www.w3.org/2001/XMLSchema#string

Jianjun Su

http://www.w3.org/2001/XMLSchema#string

Karen H Ashe

http://www.w3.org/2001/XMLSchema#string

Li-Lian Yuan

http://www.w3.org/2001/XMLSchema#string

Linda A Kotilinek

http://www.w3.org/2001/XMLSchema#string

Lorene M Lanier

http://www.w3.org/2001/XMLSchema#string

Marianne K Grant

http://www.w3.org/2001/XMLSchema#string

Miranda N Reed

http://www.w3.org/2001/XMLSchema#string

P2860

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

Mu-opioid receptors modulate the stability of dendritic spines

Reversal of long-term dendritic spine alterations in Alzheimer disease models

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

Differential regulation of dynein and kinesin motor proteins by tau

Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment

Alzheimer's disease is a synaptic failure

AMPA receptor trafficking and synaptic plasticity

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

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1067-1081

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scholarly article

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10.1016/J.NEURON.2010.11.030

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6

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68

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2010-12-01T00:00:00Z

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49697101

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21172610

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3026458

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