RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence.
about
An extended consensus motif enhances the specificity of substrate modification by SUMOSolution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognitionStructure of the 30-kDa Sin3-associated Protein (SAP30) in Complex with the Mammalian Sin3A Corepressor and Its Role in Nucleic Acid BindingRetinoblastoma-binding Protein 1 Has an Interdigitated Double Tudor Domain with DNA Binding ActivityA versatile viral system for expression and depletion of proteins in mammalian cellsAnalysis of global sumoylation changes occurring during keratinocyte differentiationIdentification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genesRetinoblastoma binding protein-1 (RBP1) is a Runx2 coactivator and promotes osteoblastic differentiation.SUMOylation of DRIL1 directs its transcriptional activity towards leukocyte lineage-specific genes.A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics.SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells.Drosophila SIN3 isoforms interact with distinct proteins and have unique biological functions.Estrogen receptor isoform-specific regulation of the retinoblastoma-binding protein 1 (RBBP1) gene: roles of AF1 and enhancer elements.Cyclin-dependent kinase-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30·mSin3·HDAC transcriptional repressor complex.Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts?Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells.PML, SUMOylation, and SenescenceRepression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts.Sin3: master scaffold and transcriptional corepressor.Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain.Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates.A chemical method for labeling lysine methyltransferase substrates.SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins.The Role of Sumoylation in Senescence.
P2860
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P2860
RBP1 family proteins exhibit SUMOylation-dependent transcriptional repression and induce cell growth inhibition reminiscent of senescence.
description
2006 nî lūn-bûn
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2006 թուականի Մարտին հրատարակուած գիտական յօդուած
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2006 թվականի մարտին հրատարակված գիտական հոդված
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@ast
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@en
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@nl
type
label
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@ast
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@en
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@nl
prefLabel
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@ast
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@en
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@nl
P2093
P2860
P1476
RBP1 family proteins exhibit S ...... ion reminiscent of senescence.
@en
P2093
Jean-Sébastien Roy
Olivier Binda
Philip E Branton
P2860
P304
P356
10.1128/MCB.26.5.1917-1931.2006
P407
P577
2006-03-01T00:00:00Z