MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
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Astrocyte elevated gene-1 induces protective autophagyMembrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cellsInhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPHMUC1-C Oncoprotein Blocks Terminal Differentiation of Chronic Myelogenous Leukemia Cells by a ROS-Mediated MechanismMucins in cancer: function, prognosis and therapyMUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cellsMucin 1 C-terminal subunit oncoprotein is a target for small-molecule inhibitors.2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase.Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.An aqueous extract of Fagonia cretica induces DNA damage, cell cycle arrest and apoptosis in breast cancer cells via FOXO3a and p53 expression.MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization.Expression of MUC17 is regulated by HIF1α-mediated hypoxic responses and requires a methylation-free hypoxia responsible element in pancreatic cancermiR-1226 targets expression of the mucin 1 oncoprotein and induces cell death.The role of the small GTPase Rab31 in cancer.MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cellsAutophagy is decreased in triple-negative breast carcinoma involving likely the MUC1-EGFR-NEU1 signalling pathway.Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cellsThe MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments.The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cellsInhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells.Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development.Activation of AMPKα mediates additive effects of solamargine and metformin on suppressing MUC1 expression in castration-resistant prostate cancer cellsMUC1 oncoprotein is a druggable target in human prostate cancer cells.MUC1-C oncoprotein promotes FLT3 receptor activation in acute myeloid leukemia cellsAutophagy inhibition enhances photocytotoxicity of Photosan-II in human colorectal cancer cells.MUC1: a novel metabolic master regulator.Autophagy and cancer metabolism.Chemotherapy treatment induces an increase of autophagy in the luminal breast cancer cell MCF7, but not in the triple-negative MDA-MB231.MUC1-C Oncoprotein Integrates a Program of EMT, Epigenetic Reprogramming and Immune Evasion in Human Carcinomas.Regulation of autophagy by glucose in Mammalian cells.Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression.Mucin 1 promotes radioresistance in hepatocellular carcinoma cells through activation of JAK2/STAT3 signaling.Regulation of Tumor Progression by Programmed Necrosis.
P2860
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P2860
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@ast
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@en
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@nl
type
label
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@ast
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@en
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@nl
prefLabel
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@ast
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@en
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@nl
P2093
P2860
P1476
MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
@en
P2093
Donald Kufe
Surender Kharbanda
P2860
P304
P577
2009-06-01T00:00:00Z