Probucol inhibits oxidative modification of low density lipoprotein. - Wikidata - awgldk - TriplyDB

Probucol inhibits oxidative modification of low density lipoprotein.

Probucol inhibits oxidative modification of low density lipoprotein.

http://www.wikidata.org/entity/Q34522551

about

Probucol for type 2 diabetes mellitus Probucol for type 2 diabetes mellitus Probucol attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin Rational drug design applied to myeloperoxidase inhibition.The role of lipid peroxidation in arteriosclerosis.Cholesteryl ester accumulation in macrophages incubated with low density lipoprotein pretreated with cigarette smoke extract Low density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis Homocyst(e)ine and heart disease: pathophysiology of extracellular matrix.Why are low-density lipoproteins atherogenic?Atherosclerosis: inhibition of regression as therapeutic possibilities Endothelial dysfunction in diabetes: pathogenesis, significance, and treatment.Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits.Abnormally high thromboxane biosynthesis in homozygous homocystinuria. Evidence for platelet involvement and probucol-sensitive mechanism Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.Inhibition by interferon-gamma of human mononuclear cell-mediated low density lipoprotein oxidation. Participation of tryptophan metabolism along the kynurenine pathway.Antioxidant: a new role for RU-486 and related compounds Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen.Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide generation.Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation?Preservation of the endogenous antioxidants in low density lipoprotein by ascorbate but not probucol during oxidative modification Renal vasoconstriction caused by short-term cholesterol feeding is corrected by thromboxane antagonist or probucol.Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atheroscleros Anti-oxidants-- a protective role in cardiovascular disease?Effect of antioxidants on oxidative modification of LDL.Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.Reactive oxygen species in cardiovascular disease.Chance and serendipity in science: two examples from my own career.Experimental and clinical studies show that the probucol derivative AGI-1067 prevents vascular growth.In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish.High preprocedural non-HDL cholesterol is associated with enhanced oxidative stress and monocyte activation after coronary angioplasty: possible implications in restenosis Stimulated arachidonate metabolism during foam cell transformation of mouse peritoneal macrophages with oxidized low density lipoprotein.Ischemic acute renal failure and antioxidant therapy in the rat. The relation between glomerular and tubular dysfunction.Lowering cholesterol, 1988. Rationale, mechanisms, and means.Evidence for an additional intracellular site of action of probucol in the prevention of oxidative modification of low density lipoprotein. Use of a new water-soluble probucol derivative.Beta-carotene inhibits atherosclerosis in hypercholesterolemic rabbits.Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit.Glycation, oxidation, and lipoxidation in the development of the complications of diabetes: a carbonyl stress hypothesis

P2860

Q24195163-79645C4E-EDD2-4203-A72C-ACE8D956297E Q24240606-ACE5979F-B012-40C7-AC3A-5BC40A067E34 Q28359752-04A86CDD-B320-4B1A-8740-07CD202A0B42 Q28538633-3C986FC4-B06A-4E8D-9948-A2019CEEC219 Q30372838-B5D51574-CFE3-4EC6-8E0E-9C60DD286E3B Q30441742-23DEFECE-E8BB-4F03-B34D-CF46071792F0 Q33564788-C09741F1-A80D-4E54-B888-135650049E5D Q33592229-CCDA99B5-28AF-427F-A671-FA5635576FF6 Q33606377-5DDD63AF-0A1D-4533-8FCE-E61A40D1AE52 Q33607440-A12DEB4B-EA50-49E3-82AF-A8D5EACDE2A6 Q33611394-CA763187-3016-4BAB-A0DB-0230F9F7CD5D Q33776230-44EB651A-4BE4-4399-9E5F-AAE603A97751 Q33855324-1BA3BE8A-5A05-4029-A4B6-C5AE75DCD1B7 Q33902343-71518BD1-E8E7-462A-AF12-1F493ED8E371 Q33905168-2211E0C1-A9B5-4356-A4AB-FAA070FD215B Q34127841-F827BD6A-CF8C-4E44-B2F5-FE687844612B Q34145731-048FE12D-8EA0-4A43-BD78-9C0EABADF21D Q34157921-F918BCFE-85AC-4184-B6AD-6194652CC174 Q34190557-FCA9A43A-8684-4F2D-88F6-5770DA4691F2 Q34223247-746AAF58-F540-443D-A75E-1EAA361DA505 Q34234638-75979E0B-F71D-4AD4-A280-281345735A31 Q34237254-4172D653-A09E-4E18-9038-03DA5AE14ECA Q34263908-1A19B3D2-7852-45DF-9CBA-CCF483BC5AD5 Q34340579-E68C0B9E-A18C-49C0-9831-36C42875EB4B Q34360883-1F1E88FE-D877-4C9C-B9A6-F2F620BB752F Q34515450-4D3B6655-4694-4BB3-8DD3-F47E4863901B Q34636198-5800EBA9-9699-4980-B0B2-6DADD970D050 Q35044177-03D7F054-1F1C-4C0D-8EC8-5E2B8BD8E371 Q35165194-A26E7D31-AFDA-435F-818E-FDE0368B6C83 Q35516016-1EA10EE3-477C-4DBF-B33B-D98B0A651B6E Q35570967-3F9F3B4B-B1AB-46D9-A5BC-7BBABC891ACD Q35578606-978D5812-64E5-440C-8FAE-BDEAC1176930 Q35581270-F89EBF9A-A99A-4D99-8C83-581BECB6808B Q35586059-AD798F57-6724-4D1E-B9F9-6CBC2CBE4670 Q35588716-62051B9B-4E03-4861-A7BE-74CCC360A972 Q35588973-C72CB1DD-BA8C-4EB9-BD06-2C361A253B9C Q35602530-7D8C7EBD-EC06-473C-A137-BE2E05CC2F8F Q35765213-BEAF24CD-7C33-45CB-BB44-97E36BD107B2 Q35817369-3877AE2F-F0B7-418B-8939-A3AA426E03D9 Q36052417-B4805E4F-5452-43EA-AEC7-3FFF73544009

P2860

Probucol inhibits oxidative modification of low density lipoprotein.

http://www.wikidata.org/entity/Q34522551

description

1986 nî lūn-bûn

@nan

1986 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

1986 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

1986年の論文

@ja

1986年論文

@yue

1986年論文

@zh-hant

1986年論文

@zh-hk

1986年論文

@zh-mo

1986年論文

@zh-tw

1986年论文

@wuu

name

Probucol inhibits oxidative modification of low density lipoprotein.

@ast

Probucol inhibits oxidative modification of low density lipoprotein.

@en

Probucol inhibits oxidative modification of low density lipoprotein.

@nl

type

label

Probucol inhibits oxidative modification of low density lipoprotein.

@ast

Probucol inhibits oxidative modification of low density lipoprotein.

@en

Probucol inhibits oxidative modification of low density lipoprotein.

@nl

prefLabel

Probucol inhibits oxidative modification of low density lipoprotein.

@ast

Probucol inhibits oxidative modification of low density lipoprotein.

@en

Probucol inhibits oxidative modification of low density lipoprotein.

@nl

P1433

Q34522551-BB2EBC77-740D-4517-95C7-B09F355E61FD

P1476

Q34522551-9F6F5B3B-6810-4A10-BF9A-89A48B8D7ED1

P2093

Q34522551-0683AF71-62BC-49BA-82CF-E94D40739FB4

Q34522551-0E2E8445-5FDD-4524-A9D1-BDDF5A16E3D1

Q34522551-6C4598E9-FC3C-43EA-A6E1-1EEB0DD28C61

Q34522551-D8DCA708-7F63-4662-8CD7-ECF45DED0BAD

Q34522551-E0003BE6-21E3-4CBD-A23C-C7587197229E

P2860

Q34522551-15AEF92D-5E43-4E22-9DA4-EFC42266444B

Q34522551-15E197E9-81DC-4318-9A47-B45CED0EEA80

Q34522551-29C2D829-0AF2-4933-852F-CBAFAA7B6466

Q34522551-383F8C43-892B-4000-A9ED-A1D7FB9E164B

Q34522551-6585F3C8-8241-42BC-9AC3-C87317EDE26B

Q34522551-68691D4C-C255-48BF-BEB6-6A23B4A8DCA5

Q34522551-704316FD-AA08-46F8-830C-4217F6E5D6D5

Q34522551-84472293-3EF5-4DAE-B0E4-7ABF0CDAE6DF

Q34522551-B09B98B1-0504-4B6F-9E19-C41F19A51ED5

Q34522551-C5B1D5DC-D684-4115-8EBC-BC198DDA1FD8

P304

Q34522551-2AACEB13-B528-403C-8DB1-A3C3BC9CBCC3

P31

Q34522551-D4E864E5-9BA3-4659-A34A-08F0013CC571

P356

Q34522551-7D7B83DD-AAE2-46DD-B164-78BF36BB45BC

P407

Q34522551-6C0ADA63-2D02-4FED-B1F1-3BACDEF3D103

P433

Q34522551-E96F5D33-ED32-4019-8D3A-56D22814D9CB

P478

Q34522551-2E3CC7A2-C883-4EB4-8E78-90A102DAC8AD

P577

Q34522551-A9E3674A-3C35-48DB-84BB-097CDC46FF5F

P5875

Q34522551-678BD59B-0BE6-4330-B93B-6986B4A2FC8B

P698

Q34522551-4EBB55B5-19C2-42BB-820A-F75C7F66669E

P921

Q34522551-3B05B4DE-16A5-4BA0-BED0-9A2163FF700B

P932

Q34522551-F8DB36E6-B587-45FB-BA05-C171284991BE

P356

P1433

Journal of Clinical Investigation

P1476

Probucol inhibits oxidative modification of low density lipoprotein.

@en

P2093

D Steinberg

http://www.w3.org/2001/XMLSchema#string

J L Witztum

http://www.w3.org/2001/XMLSchema#string

R C Pittman

http://www.w3.org/2001/XMLSchema#string

S G Young

http://www.w3.org/2001/XMLSchema#string

S Parthasarathy

http://www.w3.org/2001/XMLSchema#string

P2860

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

Arterial foam cells with distinctive immunomorphologic and histochemical features of macrophages

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

Malondialdehyde alteration of low density lipoproteins leads to cholesteryl ester accumulation in human monocyte-macrophages

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins.

Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low density lipoprotein.

Oxygen-mediated heterogeneity of apo-low-density lipoprotein.

Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein.

P304

641-644

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI112349

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

77

http://www.w3.org/2001/XMLSchema#string

P577

1986-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

19218215

http://www.w3.org/2001/XMLSchema#string

P698

3944273

http://www.w3.org/2001/XMLSchema#string

P921

P932

423406

http://www.w3.org/2001/XMLSchema#string