Plucking the high hanging fruit: a systematic approach for targeting protein-protein interactions
about
Inhibitor of MYC identified in a Kröhnke pyridine libraryProtein-Protein Interactions Mediated by Helical Tertiary Structure Motifs.In vivo modulation of hypoxia-inducible signaling by topographical helix mimetics.Anatomy of β-strands at protein-protein interfaces.Small-molecule inhibitors of protein-protein interactions: progressing toward the reality.How proteins bind macrocycles.Alternative modulation of protein-protein interactions by small moleculesNew Frontiers in DruggabilitySmall-Molecule and Peptide Inhibitors of the Pro-Survival Protein Mcl-1AlphaSpace: Fragment-Centric Topographical Mapping To Target Protein-Protein Interaction Interfaces.Advances in the synthesis of glycosidic macrolides: clavosolides A-D and cyanolide A.High-resolution structures of a heterochiral coiled coilScreening-based approaches to identify small molecules that inhibit protein-protein interactions.Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.Flexibility and small pockets at protein-protein interfaces: New insights into druggability.HippDB: a database of readily targeted helical protein-protein interactions.Oncogenic protein interfaces: small molecules, big challenges.Direct targeting of Rab-GTPase-effector interactions.Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.Synthesis of hydrogen-bond surrogate α-helices as inhibitors of protein-protein interactions.The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1.RNA Polymerase Tags To Monitor Multidimensional Protein-Protein Interactions Reveal Pharmacological Engagement of Bcl-2 Proteins.Protein Domain Mimics as Modulators of Protein-Protein Interactions.Bridged bicyclic peptides as potential drug scaffolds: synthesis, structure, protein binding and stability.
P2860
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P2860
Plucking the high hanging fruit: a systematic approach for targeting protein-protein interactions
description
2012 nî lūn-bûn
@nan
2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Plucking the high hanging frui ...... g protein-protein interactions
@ast
Plucking the high hanging frui ...... g protein-protein interactions
@en
Plucking the high hanging frui ...... g protein-protein interactions
@nl
type
label
Plucking the high hanging frui ...... g protein-protein interactions
@ast
Plucking the high hanging frui ...... g protein-protein interactions
@en
Plucking the high hanging frui ...... g protein-protein interactions
@nl
prefLabel
Plucking the high hanging frui ...... g protein-protein interactions
@ast
Plucking the high hanging frui ...... g protein-protein interactions
@en
Plucking the high hanging frui ...... g protein-protein interactions
@nl
P2093
P2860
P1476
Plucking the high hanging frui ...... g protein-protein interactions
@en
P2093
Brooke N Bullock
Monika Raj
Paramjit S Arora
P2860
P304
P356
10.1016/J.BMC.2012.11.023
P407
P577
2012-12-04T00:00:00Z