Gene therapy for rheumatoid arthritis. Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators.
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Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: a strategy to promote cartilage repairA model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKLThe active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytesAdenovirus-mediated gene transfer of interleukin-4 into pancreatic stellate cells promotes interleukin-10 expressionEarly gestational gene transfer of IL-10 by systemic administration of lentiviral vector can prevent arthritis in a murine model.Temporal expression and tissue distribution of interleukin-1β in two strains of guinea pigs with varying propensity for spontaneous knee osteoarthritis.Metalloproteinases: their role in arthritis and potential as therapeutic targets.Gene therapy in nonhuman primate models of human autoimmune disease.Interferon beta stimulates interleukin 1 receptor antagonist production in human articular chondrocytes and synovial fibroblastsAseptic loosening of total joint replacements: mechanisms underlying osteolysis and potential therapies.Host persistence: exploitation of anti-inflammatory pathways by Toxoplasma gondii.IL10 released by a new inflammation-regulated lentiviral system efficiently attenuates zymosan-induced arthritisRole of the NF-kappaB axis in immune modulation of osteoclasts and bone loss.Synthesis of self-assembled IL-1Ra-presenting nanoparticles for the treatment of osteoarthritis.Experimental study of local inner ear gene therapy for controlling autoimmune sensorineural hearing loss.Adenoviral gene transfer of interleukin-1 in combination with oncostatin M induces significant joint damage in a murine model.In vivo reduction or blockade of interleukin-1β in primary osteoarthritis influences expression of mediators implicated in pathogenesis.An inflammation-inducible adenoviral expression system for local treatment of the arthritic joint.Application of a disease-regulated promoter is a safer mode of local IL-4 gene therapy for arthritis.Protective effects of IL-1Ra or vIL-10 gene transfer on a murine model of wear debris-induced osteolysis.Prevention of experimental autoimmune encephalomyelitis in DA rats by grafting primary skin fibroblasts engineered to express transforming growth factor-beta1.Phosphatidylserine-containing liposomes suppress inflammatory bone loss by ameliorating the cytokine imbalance provoked by infiltrated macrophages.
P2860
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P2860
Gene therapy for rheumatoid arthritis. Lessons from animal models, including studies on interleukin-4, interleukin-10, and interleukin-1 receptor antagonist as potential disease modulators.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Gene therapy for rheumatoid ar ...... potential disease modulators.
@ast
Gene therapy for rheumatoid ar ...... potential disease modulators.
@en
Gene therapy for rheumatoid ar ...... potential disease modulators.
@nl
type
label
Gene therapy for rheumatoid ar ...... potential disease modulators.
@ast
Gene therapy for rheumatoid ar ...... potential disease modulators.
@en
Gene therapy for rheumatoid ar ...... potential disease modulators.
@nl
prefLabel
Gene therapy for rheumatoid ar ...... potential disease modulators.
@ast
Gene therapy for rheumatoid ar ...... potential disease modulators.
@en
Gene therapy for rheumatoid ar ...... potential disease modulators.
@nl
P1476
Gene therapy for rheumatoid ar ...... potential disease modulators.
@en
P2093
Fons A J van de Loo
Wim B van den Berg
P304
P356
10.1016/S0889-857X(03)00073-5
P577
2002-02-01T00:00:00Z