Discovery of New Human A(2A) Adenosine Receptor Agonists: Design, Synthesis, and Binding Mode of Truncated 2-Hexynyl-4'-thioadenosine.

Discovery of New Human A(2A) Adenosine Receptor Agonists: Design, Synthesis, and Binding Mode of Truncated 2-Hexynyl-4'-thioadenosine.

Item
http://www.wikidata.org/entity/Q34536571
Probing biased/partial agonism at the G protein-coupled A(2B) adenosine receptor.Truncated (N)-Methanocarba Nucleosides as A(1) Adenosine Receptor Agonists and Partial Agonists: Overcoming Lack of a Recognition ElementMolecular docking screening using agonist-bound GPCR structures: probing the A2A adenosine receptor.Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.Structure-activity relationships of truncated C2- or C8-substituted adenosine derivatives as dual acting A₂A and A₃ adenosine receptor ligands.Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activitySynthesis and anti-renal fibrosis activity of conformationally locked truncated 2-hexynyl-N(6)-substituted-(N)-methanocarba-nucleosides as A3 adenosine receptor antagonists and partial agonists.Determination and validation of LJ-2698, a potent human A3 adenosine receptor antagonist, in rat plasma by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study.New selective A2A agonists and A3 antagonists for human adenosine receptors: synthesis, biological activity and molecular docking studies
P2860

Discovery of New Human A(2A) Adenosine Receptor Agonists: Design, Synthesis, and Binding Mode of Truncated 2-Hexynyl-4'-thioadenosine.

Item
http://www.wikidata.org/entity/Q34536571
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@ast
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@en
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@nl
type
label
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@ast
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@en
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@nl
prefLabel
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@ast
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@en
Discovery of New Human A(2A) A ...... ed 2-Hexynyl-4'-thioadenosine.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Discovery of New Human A(2A) A ...... ted 2-Hexynyl-4'-thioadenosine
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P932