Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions.
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The Closing Mechanism of DNA Polymerase I at Atomic ResolutionX-ray crystal structures elucidate the nucleotidyl transfer reaction of transcript initiation using two nucleotides.The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray CrystallographyFluorescence resonance energy transfer studies of DNA polymerase β: the critical role of fingers domain movements and a novel non-covalent step during nucleotide selection.Kinetic analysis of the unique error signature of human DNA polymerase ν.Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection.Modulation of DNA Polymerase Noncovalent Kinetic Transitions by Divalent CationsMeasuring and modeling the kinetics of individual DNA-DNA polymerase complexes on a nanoporeConformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion.Prechemistry nucleotide selection checkpoints in the reaction pathway of DNA polymerase I and roles of glu710 and tyr766.The DnaE polymerase from Deinococcus radiodurans features RecA-dependent DNA polymerase activityMagnesium physiology and clinical therapy in veterinary critical care.Time-resolved events on the reaction pathway of transcript initiation by a single-subunit RNA polymerase: Raman crystallographic evidence.dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state.Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity.The thumb domain is not essential for the catalytic action of HoLaMa DNA polymerase.Computational Simulations of DNA Polymerases: Detailed Insights on Structure/Function/Mechanism from Native Proteins to Cancer Variants.I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity
P2860
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P2860
Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions.
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Distinct roles of the active-s ...... ry conformational transitions.
@ast
Distinct roles of the active-s ...... ry conformational transitions.
@en
Distinct roles of the active-s ...... ry conformational transitions.
@nl
type
label
Distinct roles of the active-s ...... ry conformational transitions.
@ast
Distinct roles of the active-s ...... ry conformational transitions.
@en
Distinct roles of the active-s ...... ry conformational transitions.
@nl
prefLabel
Distinct roles of the active-s ...... ry conformational transitions.
@ast
Distinct roles of the active-s ...... ry conformational transitions.
@en
Distinct roles of the active-s ...... ry conformational transitions.
@nl
P2093
P2860
P356
P1476
Distinct roles of the active-s ...... ry conformational transitions.
@en
P2093
Catherine M Joyce
Nigel D F Grindley
Oya Bermek
P2860
P304
P356
10.1074/JBC.M110.167593
P407
P577
2010-11-16T00:00:00Z