Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
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Differences in LexA regulon structure among Proteobacteria through in vivo assisted comparative genomicsStructural basis for transcription inhibition by tagetitoxinQM/MM molecular dynamics studies of metal binding proteinsHuman DNA Polymerase η Is Pre-Aligned for dNTP Binding and CatalysisUnfavorable Electrostatic and Steric Interactions in DNA Polymerase β E295K Mutant Interfere with the Enzyme’s PathwayStructural Basis for Promutagenicity of 8-Halogenated GuanineMetal-Dependent Conformational Activation Explains Highly Promutagenic Replication across O6-Methylguanine by Human DNA Polymerase βThe significance of Mg in prebiotic geochemistryCharacterization of the SOS regulon of Caulobacter crescentus.Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selectionEffect of A and B metal ion site occupancy on conformational changes in an RB69 DNA polymerase ternary complex.Fidelity of Dpo4: effect of metal ions, nucleotide selection and pyrophosphorolysis.The use of divalent metal ions by type II topoisomerases.Ultrafast water dynamics at the interface of the polymerase-DNA binding complexIn silico evidence for DNA polymerase-beta's substrate-induced conformational changeIn silico studies of the African swine fever virus DNA polymerase X support an induced-fit mechanismEffect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus.Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions.Energy analysis of chemistry for correct insertion by DNA polymerase beta.Sequential side-chain residue motions transform the binary into the ternary state of DNA polymerase lambda.DNA pol λ's extraordinary ability to stabilize misaligned DNA.Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase betaMagnesium-induced assembly of a complete DNA polymerase catalytic complex.Polymerase-catalyzed synthesis of DNA from phosphoramidate conjugates of deoxynucleotides and amino acids.Dynamic conformational heterogeneities of carcinogen-DNA adducts and their mutagenic relevance.An abridged transition state model to derive structure, dynamics, and energy components of DNA polymerase β fidelity.Magnesium intake and incidence of pancreatic cancer: the VITamins and Lifestyle studyPerspective: pre-chemistry conformational changes in DNA polymerase mechanismsHuman topoisomerase IIalpha uses a two-metal-ion mechanism for DNA cleavage.Insertion of oxidized nucleotide triggers rapid DNA polymerase openingMultifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms.Magnetic isotope and magnetic field effects on the DNA synthesis.Relationship between conformational changes in pol lambda's active site upon binding incorrect nucleotides and mismatch incorporation rates.How DNA polymerase X preferentially accommodates incoming dATP opposite 8-oxoguanine on the template.Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.Different Divalent Cations Alter the Kinetics and Fidelity of DNA Polymerases.Mismatched base-pair simulations for ASFV Pol X/DNA complexes help interpret frequent G*G misincorporation.DNA stabilization at the Bacillus subtilis PolX core--a binding model to coordinate polymerase, AP-endonuclease and 3'-5' exonuclease activities.Dynamics of nucleotide incorporation: snapshots revealed by 2-aminopurine fluorescence studies.Exploring the mechanism of DNA polymerases by analyzing the effect of mutations of active site acidic groups in Polymerase β
P2860
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P2860
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@ast
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@en
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@nl
type
label
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@ast
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@en
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@nl
prefLabel
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@ast
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@en
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@nl
P2093
P3181
P356
P1476
Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly
@en
P2093
Karunesh Arora
Linjing Yang
Samuel H Wilson
William A Beard
P304
P3181
P356
10.1021/JA049412O
P407
P577
2004-07-14T00:00:00Z