ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. - Wikidata - awgldk - TriplyDB

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

http://www.wikidata.org/entity/Q34539617

about

Molecular mechanisms of ETS transcription factor-mediated tumorigenesis ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells ELF5 isoform expression is tissue-specific and significantly altered in cancer.Minireview: prolactin regulation of adult stem cells The innate and adaptive infiltrating immune systems as targets for breast cancer immunotherapy.TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis.A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia.Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer The mammary cellular hierarchy and breast cancer.The ETS family of oncogenic transcription factors in solid tumours.Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells.RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.Humanization of the mouse mammary gland by replacement of the luminal layer with genetically engineered preneoplastic human cells Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer Regulators of genetic risk of breast cancer identified by integrative network analysis.ELF5 and DOK7 regulation in anti-estrogen treated cells and tumors.Modeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse.Elf5 - breast cancer's little helper PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells.The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression.Breast cancer stem cells.Hormone-sensing mammary epithelial progenitors: emerging identity and hormonal regulation.Methyl-CpG-binding protein MBD2 plays a key role in maintenance and spread of DNA methylation at CpG islands and shores in cancer.ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype.Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation.Fibroblast Subtypes Regulate Responsiveness of Luminal Breast Cancer to Estrogen.Endometrial Cancer-Associated FGF18 Expression Is Reduced by Bazedoxifene in Human Endometrial Stromal Cells In Vitro and in Murine Endometrium.ELF5 in epithelial ovarian carcinoma tissues and biological behavior in ovarian carcinoma cells.ESE-1/ELF3 mRNA expression associates with poor survival outcomes in HER2+ breast cancer patients and is critical for tumorigenesis in HER2+ breast cancer cells.Inhibition of lobuloalveolar development by FOXC1 overexpression in the mouse mammary gland.Age-related gene expression in luminal epithelial cells is driven by a microenvironment made from myoepithelial cells.NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma.Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis.ELF3, ELF5, EHF and SPDEF Transcription Factors in Tissue Homeostasis and Cancer

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P2860

ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.

http://www.wikidata.org/entity/Q34539617

description

2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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ELF5 suppresses estrogen sensi ...... ance in luminal breast cancer.

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JOURNAL.PBIO.1001461

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ELF5 suppresses estrogen sensi ...... tance in luminal breast cancer

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Aaron L Statham

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Adelaide Young

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Andrea Egger

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Andrew Stone

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Anita Ledger

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C Elizabeth Caldon

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Cara J Evans

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Christopher J Ormandy

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Daniel L Roden

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David Gallego-Ortega

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Model-based analysis of ChIP-Seq (MACS)

A novel transcription factor, ELF5, belongs to the ELF subfamily of ETS genes and maps to human chromosome 11p13-15, a region subject to LOH and rearrangement in human carcinoma cell lines

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts.

A gene-expression signature as a predictor of survival in breast cancer

Molecular portraits of human breast tumours

Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning

Socs2 and elf5 mediate prolactin-induced mammary gland development

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

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10.1371/JOURNAL.PBIO.1001461

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12

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10

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Alexander Swarbrick

Samantha R Oakes

Catherine L Piggin

Nicola J Armstrong

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2012-12-27T00:00:00Z

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234089981

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23300383

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3531499

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