RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.
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Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven CancersRunx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition.Runx1 is associated with breast cancer progression in MMTV-PyMT transgenic mice and its depletion in vitro inhibits migration and invasionRunx2 contributes to the regenerative potential of the mammary epithelium.Dendrobium candidum inhibits MCF-7 cells proliferation by inducing cell cycle arrest at G2/M phase and regulating key biomarkersRUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer.MicroRNA-378-mediated suppression of Runx1 alleviates the aggressive phenotype of triple-negative MDA-MB-231 human breast cancer cells.Erianin inhibits the proliferation of T47D cells by inhibiting cell cycles, inducing apoptosis and suppressing migrationChromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles.Hormone-sensing mammary epithelial progenitors: emerging identity and hormonal regulation.Relationship between RUNX1 and AXIN1 in ER-negative versus ER-positive Breast Cancer.The Emerging Roles of RUNX Transcription Factors in Epithelial-Mesenchymal Transition.Runx Family Genes in Tissue Stem Cell Dynamics.Runx Genes in Breast Cancer and the Mammary Lineage.Deletion of Interstitial Genes between TMPRSS2 and ERG Promotes Prostate Cancer Progression.Pathobiology of the 129:Stat1 -/- mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotypeRUNX1 and breast cancer.Prolactin Alters the Mammary Epithelial Hierarchy, Increasing Progenitors and Facilitating Ovarian Steroid ActionRUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells.Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing.Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α.BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells.Roles of RUNX in Solid Tumors.RUNX1 and RUNX3 protect against YAP-mediated EMT, stem-ness and shorter survival outcomes in breast cancer.is a RUNX1 target gene and promotes migration of NSCLC cells
P2860
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P2860
RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.
description
2014 nî lūn-bûn
@nan
2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@ast
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@en
type
label
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@ast
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@en
prefLabel
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@ast
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@en
P2093
P2860
P356
P1433
P1476
RUNX1, a transcription factor ...... ositive mammary luminal cells.
@en
P2093
Maaike P A van Bragt
P2860
P304
P356
10.7554/ELIFE.03881
P407
P577
2014-11-21T00:00:00Z