Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.
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Repression of HMGA2 gene expression by human cytomegalovirus involves the IE2 86-kilodalton protein and is necessary for efficient viral replication and inhibition of cyclin A transcriptionNeuropathogenesis of congenital cytomegalovirus infection: disease mechanisms and prospects for interventionHuman cytomegalovirus protein pUL117 targets the mini-chromosome maintenance complex and suppresses cellular DNA synthesis.Human cytomegalovirus gene UL21a encodes a short-lived cytoplasmic protein and facilitates virus replication in fibroblastsEnhancement of enteric adenovirus cultivation by viral transactivator proteinsDepletion of cellular pre-replication complex factors results in increased human cytomegalovirus DNA replication.The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirusAlternative splicing of the human cytomegalovirus major immediate-early genes affects infectious-virus replication and control of cellular cyclin-dependent kinase.Host-viral effects of chromatin assembly factor 1 interaction with HCMV IE2Mutation of glutamine to arginine at position 548 of IE2 86 in human cytomegalovirus leads to decreased expression of IE2 40, IE2 60, UL83, and UL84 and increased transcription of US8-9 and US29-32.The human cytomegalovirus UL133-138 gene locus attenuates the lytic viral cycle in fibroblasts.Proteomic profiling of the human cytomegalovirus UL35 gene products reveals a role for UL35 in the DNA repair responseThe autoregulatory and transactivating functions of the human cytomegalovirus IE86 protein use independent mechanisms for promoter binding.The full-length protein encoded by human cytomegalovirus gene UL117 is required for the proper maturation of viral replication compartments.Cell cycle-independent expression of immediate-early gene 3 results in G1 and G2 arrest in murine cytomegalovirus-infected cells.Regulation of the retinoblastoma proteins by the human herpesviruses.The CREB site in the proximal enhancer is critical for cooperative interaction with the other transcription factor binding sites to enhance transcription of the major intermediate-early genes in human cytomegalovirus-infected cells.Congenital cytomegalovirus infection: molecular mechanisms mediating viral pathogenesis.The human cytomegalovirus major immediate-early proteins as antagonists of intrinsic and innate antiviral host responses.Biology and pathogenesis of cytomegalovirus in periodontal disease.Human Cytomegalovirus IE2 Protein Disturbs Brain Development by the Dysregulation of Neural Stem Cell Maintenance and the Polarization of Migrating Neurons.Development of cell lines that provide tightly controlled temporal translation of the human cytomegalovirus IE2 proteins for complementation and functional analyses of growth-impaired and nonviable IE2 mutant viruses.Internal deletions of IE2 86 and loss of the late IE2 60 and IE2 40 proteins encoded by human cytomegalovirus affect the levels of UL84 protein but not the amount of UL84 mRNA or the loading and distribution of the mRNA on polysomesHuman cytomegalovirus downregulates SLITRK6 expression through IE2.The presence of p53 influences the expression of multiple human cytomegalovirus genes at early times postinfectionHuman cytomegalovirus early protein pUL21a promotes efficient viral DNA synthesis and the late accumulation of immediate-early transcripts.Human cytomegalovirus and Herpes Simplex type I virus can engage RNA polymerase I for transcription of immediate early genes.
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Inhibition of cellular DNA synthesis by the human cytomegalovirus IE86 protein is necessary for efficient virus replication.
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2006 nî lūn-bûn
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2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2006 թվականի ապրիլին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Inhibition of cellular DNA syn ...... r efficient virus replication.
@ast
Inhibition of cellular DNA syn ...... r efficient virus replication.
@en
Inhibition of cellular DNA syn ...... r efficient virus replication.
@nl
type
label
Inhibition of cellular DNA syn ...... r efficient virus replication.
@ast
Inhibition of cellular DNA syn ...... r efficient virus replication.
@en
Inhibition of cellular DNA syn ...... r efficient virus replication.
@nl
prefLabel
Inhibition of cellular DNA syn ...... r efficient virus replication.
@ast
Inhibition of cellular DNA syn ...... r efficient virus replication.
@en
Inhibition of cellular DNA syn ...... r efficient virus replication.
@nl
P2093
P2860
P1433
P1476
Inhibition of cellular DNA syn ...... r efficient virus replication.
@en
P2093
Dustin T Petrik
Kimberly P Schmitt
Mark F Stinski
P2860
P304
P356
10.1128/JVI.80.8.3872-3883.2006
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P577
2006-04-01T00:00:00Z