Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model. - Wikidata - awgldk - TriplyDB

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.

http://www.wikidata.org/entity/Q34551206

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Signaling Interplay between Bone Marrow Adipose Tissue and Multiple Myeloma cells MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment High throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomib Soluble Factors on Stage to Direct Mesenchymal Stem Cells Fate.Ex Vivo Maintenance of Primary Human Multiple Myeloma Cells through the Optimization of the Osteoblastic Niche.Primary myeloma interaction and growth in coculture with healthy donor hematopoietic bone marrow.Dynamic interplay between bone and multiple myeloma: emerging roles of the osteoblast Surface-tension driven open microfluidic platform for hanging droplet culture.Multiple myeloma in the marrow: pathogenesis and treatments.Navigating the bone marrow niche: translational insights and cancer-driven dysfunction.Innovative approaches to establish and characterize primary cultures: an ex vivo 3D system and the zebrafish model.A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications.The osteoblastic niche in the context of multiple myeloma.Three dimensional de novo micro bone marrow and its versatile application in drug screening and regenerative medicine.Myeloma and Bone Disease.The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis.3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma.Adipose, Bone, and Myeloma: Contributions from the Microenvironment.Tissue-engineered 3D cancer-in-bone modeling: silk and PUR protocols MicroRNA Transfer Between Bone Marrow Adipose and Multiple Myeloma Cells.Drug discovery and therapeutic delivery for the treatment of B and T cell tumors.Engineering 3D Models of Tumors and Bone to Understand Tumor-Induced Bone Disease and Improve Treatments.3D tissue-engineered bone marrow: what does this mean for the treatment of multiple myeloma?Evolutionary biology of high-risk multiple myeloma.CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma.Secreted factors from metastatic prostate cancer cells stimulate mesenchymal stem cell transition to a pro-tumourigenic 'activated' state that enhances prostate cancer cell migration.Reflections on Cancer in the Bone Marrow: Adverse Roles of Adipocytes.Development of a 3D bone marrow adipose tissue model.Modeling Multiple Myeloma-Bone Marrow interactions and response to drugs in a 3D surrogate microenvironment.The bone-marrow niche in MDS and MGUS: implications for AML and MM.New agents in the Treatment of Myeloma Bone Disease.Tissue Engineering Platforms to Replicate the Tumor Microenvironment of Multiple Myeloma.Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks.How to Hit Mesenchymal Stromal Cells and Make the Tumor Microenvironment Immunostimulant Rather Than Immunosuppressive.Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model.3d Tissue Engineered In Vitro Models Of Cancer In Bone

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Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model.

http://www.wikidata.org/entity/Q34551206

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Investigating osteogenic diffe ...... el 3D bone marrow niche model.

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Investigating osteogenic diffe ...... el 3D bone marrow niche model.

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Investigating osteogenic diffe ...... el 3D bone marrow niche model.

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Irene M Ghobrial

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Jiantao Shi

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John E Ready

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Masoumeh Memarzadeh

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Salomon Manier

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Yong Zhang

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Yosra Aljawai

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Yu Zhang

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Yu-Tzu Tai

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Yuji Mishima

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Suppression of bone formation by osteoclastic expression of semaphorin 4D

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Flexible and versatile as a chameleon-sophisticated functions of microRNA-199a

miR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1

Statistical significance for genomewide studies

Deconstructing the third dimension: how 3D culture microenvironments alter cellular cues

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth

Ex-vivo dynamic 3-D culture of human tissues in the RCCS™ bioreactor allows the study of Multiple Myeloma biology and response to therapy

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.

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3250-3259

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10.1182/BLOOD-2014-02-558007

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Michaela R. Reagan

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