PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.
about
Going beyond genetics to discover cancer targetsHistone H3 lysine 4 methyltransferase KMT2D.The PI3K Pathway in Human Disease.PLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC.FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST).KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.Advances in the management of HER2-positive early breast cancer.Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors.DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.Phosphatidylinositol 3-Kinase α-Selective Inhibition With Alpelisib (BYL719) in PIK3CA-Altered Solid Tumors: Results From the First-in-Human Study.Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets.Cancer epigenetics: Moving forward.Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer.WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapySignaling pathways and steroid receptors modulating estrogen receptor α function in breast cancerThe mutational landscape of recurrent versus nonrecurrent human papillomavirus-related oropharyngeal cancerPhase II Study of Taselisib (GDC-0032) in Combination with Fulvestrant in Patients with HER2-Negative, Hormone Receptor-Positive Advanced Breast CancerA novel somatic mutation of SIN3A detected in breast cancer by whole-exome sequencing enhances cell proliferation through ERα expressionGenomic case report of a low grade bladder tumor metastasis to lung
P2860
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P2860
PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.
description
2017 nî lūn-bûn
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2017 թուականի Մարտին հրատարակուած գիտական յօդուած
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2017 թվականի մարտին հրատարակված գիտական հոդված
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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name
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@ast
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@en
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@nl
type
label
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@ast
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@en
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@nl
prefLabel
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@ast
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@en
PI3K pathway regulates ER-depe ...... he epigenetic regulator KMT2D.
@nl
P2860
P50
P356
P1433
P1476
PI3K pathway regulates ER-depe ...... the epigenetic regulator KMT2D
@en
P2093
Maura N Dickler
P2860
P304
P356
10.1126/SCIENCE.AAH6893
P407
P50
P577
2017-03-01T00:00:00Z