about
Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα InhibitionPI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer.PI3K inhibition results in enhanced estrogen receptor function and dependence in hormone receptor-positive breast cancer.The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epitheliumRationale-based therapeutic combinations with PI3K inhibitors in cancer treatmentSomatic PIK3CA mutations as a driver of sporadic venous malformations.The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growthPIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.Therapeutic Benefit of Selective Inhibition of p110α PI3-Kinase in Pancreatic Neuroendocrine TumorsSystematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer.The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth.The emerging role of serum/glucocorticoid-regulated kinases in cancer.A novel vascular tumor characterized by co-existing HRAS and GNAQ activating mutationsRIT1 oncoproteins escape LZTR1-mediated proteolysisThe duality of human oncoproteins: drivers of cancer and congenital disorders
P50
Q27853093-03FA3235-5FEA-4902-8DFF-14592E78E6D3Q28118735-B2EFD066-2F91-44BD-92A5-822AAC898C3DQ34554022-987BE358-9D2D-44A2-A22D-B29DB09EC409Q34813272-139D3E30-622F-4BC6-BDA7-C76C9C170B97Q35610581-B9DEDADA-9726-4662-90F9-157219878048Q36539705-1FE06C16-44B5-4BD3-8C52-D4CC64BF9EC3Q36997524-7AF83D43-885D-431A-A53C-CB9C175401D0Q37130685-2272446A-15D1-4F5E-93E8-DC7EB2795615Q37223549-ACA78B41-601B-4767-98C9-013FB982AB13Q38735131-BBFE6C05-3153-424F-BD9E-5A6A43500E0CQ39735943-F91B9242-97C4-4E81-9D24-818D9FBE5A8FQ40591054-D190C023-7790-467B-A1BF-63E1730F653AQ41497888-6C7F1F24-E41F-4CE7-919A-249B4474D422Q41728566-00FFB8C2-60F1-4505-9374-DD2CF5154155Q58615667-D9195D6C-8BBC-459C-A28A-A29F65619FA4Q92370778-2259B22F-4CDC-4993-B021-89C5701B20BAQ93270879-65B661AD-6C99-4A08-9042-974EE8B5760F
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Pau Castel
@ast
Pau Castel
@en
Pau Castel
@es
Pau Castel
@nl
Pau Castel
@sl
type
label
Pau Castel
@ast
Pau Castel
@en
Pau Castel
@es
Pau Castel
@nl
Pau Castel
@sl
prefLabel
Pau Castel
@ast
Pau Castel
@en
Pau Castel
@es
Pau Castel
@nl
Pau Castel
@sl
P106
P21
P31
P496
0000-0002-4972-4347
P569
2000-01-01T00:00:00Z