TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition. - Wikidata - awgldk - TriplyDB

TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition.

TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition.

http://www.wikidata.org/entity/Q34555024

about

Substrate specificity and effect on GLUT4 translocation of the Rab GTPase-activating protein Tbc1d1 Obesity genetics in mouse and human: back and forth, and back again Genetic and epigenetic control of metabolic health Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation Probabilistic models of genetic variation in structured populations applied to global human studies Identification and characterization of a novel Rab GTPase-activating protein in spermatids Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane Genetic disruption of AMPK signaling abolishes both contraction- and insulin-stimulated TBC1D1 phosphorylation and 14-3-3 binding in mouse skeletal muscle Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups Rab GAPs AS160 and Tbc1d1 play nonredundant roles in the regulation of glucose and energy homeostasis in mice Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid, and energy homeostasis in mice Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle.Genomic insights into early-onset obesity.Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training.Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.The genetic basis of obesity-associated type 2 diabetes (diabesity) in polygenic mouse models Fine-scale genetic correlates to condition and migration in a wild cervid Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis.Human cardiovascular disease IBC chip-wide association with weight loss and weight regain in the look AHEAD trial.Structural and population-based evaluations of TBC1D1 p.Arg125Trp Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic Mice with AS160/TBC1D4-Thr649Ala knockin mutation are glucose intolerant with reduced insulin sensitivity and altered GLUT4 trafficking.Exercise increases TBC1D1 phosphorylation in human skeletal muscle.Genome-wide association study of body weight in chicken F2 resource population Molecular basis of obesity: current status and future prospects Genetics of Obesity: What have we Learned?Sex-, diet-, and cancer-dependent epistatic effects on complex traits in mice Association of the FTO gene with BMI.Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing.Sex differences in human adipose tissues - the biology of pear shape Whole-Genome Resequencing of Holstein Bulls for Indel Discovery and Identification of Genes Associated with Milk Composition Traits in Dairy Cattle.A Copy Number Variant on Chromosome 20q13.3 Implicated in Thinness and Severe Obesity.AMPK and Exercise: Glucose Uptake and Insulin Sensitivity.Regulatory mode shift of Tbc1d1 is required for acquisition of insulin-responsive GLUT4-trafficking activity.Five linkage regions each harbor multiple type 2 diabetes genes in the African American subset of the GENNID Study.Disruption of the AMPK-TBC1D1 nexus increases lipogenic gene expression and causes obesity in mice via promoting IGF1 secretion.TDP-43, an ALS linked protein, regulates fat deposition and glucose homeostasis.

P2860

Q24683047-C9194223-D6D5-4CBF-BEE4-EC195D90F0BC Q26782027-3B56C2D4-911E-4F0B-8161-118F8B9D374E Q27026287-B043CA19-E53F-4C37-AF03-91430B277421 Q27310317-6B8BB817-6AF7-48F3-8366-DF936C8D26C5 Q28389960-0E1D4360-31D8-4E29-8B0B-BF8AD8394D67 Q28510058-8398312B-42C5-4B81-96C4-B13A00C5C86B Q28510627-18FDDEBA-4C97-4EB5-878B-E87AF19AD1E5 Q28580015-54C59B39-92DB-44BF-83B2-65C0120FA2E1 Q28584725-D26955BA-26B4-41F0-B203-A681385D3466 Q28591941-6F5087FE-A015-459E-B246-2555E49A99B8 Q28943490-55008940-67AD-4FF6-90CD-BF4F71B4D001 Q30277981-F60AA7B0-3593-4ECF-8CF2-C7C080043E14 Q30279290-19EC4341-7947-40F4-B277-EBDC94418278 Q33675871-79E59BB3-4D35-49C9-80BA-DAACD84E8708 Q33869742-04F35173-87DE-4AB8-B203-FF32B5C0D6A0 Q33999488-1F1801BB-5EA1-4848-A5BF-2D98F042F5F3 Q34031701-805B17F3-6183-4BFE-9C78-D5DF39556105 Q34136356-B8DBAAD2-02FF-4675-A782-C1CF652B1FCA Q34185200-6AE6E988-E446-4A82-9CF6-20A1F01EFD1B Q34414771-7D7A4109-4EDF-481F-A325-8C6A57CCDD18 Q34629081-13196FEE-4C45-445A-B70C-6659DD9ABF53 Q34641723-8E5FC6A0-2C85-4988-83CA-6F513287F688 Q34718482-39F2014C-7427-48FB-9E3E-1A8DF654AA7A Q34778453-C8AD3664-C2CE-43AE-884C-FDE2153E95D0 Q34837082-E0377BAC-6539-4583-8ED6-EC8CA2019E75 Q35086804-BB674C7B-AFB9-45E9-A6DE-2FCECAA28778 Q35105797-74D6F30D-2271-4555-A8BC-56D7B6967EFD Q35107257-604A646D-5EE8-4CA1-A747-56C7DB43B1CE Q35107260-A87BA3CE-842B-4FBD-A5AC-46436615E8BE Q35711408-1181DEA7-D397-4B54-9233-39F5544D34B3 Q35767016-AA3E2F7F-CAE9-4832-B146-AC0E38519BC1 Q35909486-F2CA0C36-6D08-426E-B891-AB49B793AA9F Q36138909-AF93C652-292D-4807-B12E-C17057180525 Q36234842-A50D4965-F80E-44CB-9C2F-AEA640520394 Q36529146-AB0D689A-7063-4C2B-B2B3-53209FB48367 Q36628896-72D3B8AF-C3D8-4F51-98A5-69455AFFE018 Q36680563-57BF12DB-2DC8-4543-9BE2-696D16CE55CE Q36955084-74393EFA-53FF-4C04-B10C-C75EA34B7C80 Q37065157-CAB6B1E9-9F94-468D-9E66-C5640EB4C4C7 Q37092789-DDA174EA-E88B-41A2-A10B-06A678751FF3

P2860

TBC1D1 is a candidate for a severe obesity gene and evidence for a gene/gene interaction in obesity predisposition.

http://www.wikidata.org/entity/Q34555024

description

2006 nî lūn-bûn

@nan

2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年学术文章

@wuu

2006年学术文章

@zh-cn

2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

name

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@ast

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@en

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@nl

type

label

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@ast

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@en

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@nl

prefLabel

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@ast

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@en

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@nl

P1433

Q34555024-A9D2B6FC-0A6A-4443-B688-B794F231D693

P1476

Q34555024-2E9CE8C9-2ACD-4B5A-AB14-27E4B37FAB6A

P2093

Q34555024-079C8915-4818-4352-BA6A-BACBABA8D4E9

Q34555024-143D4DBC-B9C8-4E33-84ED-37B8282AA40F

Q34555024-2CFAC9A1-2853-4116-B74F-F93E7B19F3E2

Q34555024-313853AB-479C-455E-823F-798AF13FFD7D

Q34555024-35A038F4-8E65-4837-83D1-FC0DF2930CE8

Q34555024-3C3716E2-595E-4210-81A7-0E5F3C0E6E58

Q34555024-51431E49-816F-4CB8-BAC2-9CCA3CF10571

Q34555024-5F027013-F170-4507-86CE-85A889A844BA

Q34555024-6C6A28CE-12BB-4622-B086-DD2FEFB194BE

Q34555024-A37CBBCB-C523-4674-8438-227072F1C5A4

P2860

Q34555024-01529E9A-F156-4E48-A265-2823316733B3

Q34555024-05C3762C-432C-474C-A3B0-D397387F8922

Q34555024-06B628C2-D9B1-42F5-B6FC-90A7D8DCD08B

Q34555024-0BAD0615-3594-447A-9E0A-0EDE892547B2

Q34555024-0DCA8F0F-3E8E-4ECF-B626-D9C866627312

Q34555024-0F5BDE49-30EA-4999-8538-9733E266B48F

Q34555024-1B909625-CC99-4852-AF0C-F6924FA9892F

Q34555024-1F1422E5-6A29-4A69-BE37-AB077153AB7D

Q34555024-210AB39A-ED8B-4901-B421-492F184E0D8D

Q34555024-24E1064D-A96E-4EB7-9FF8-1B25144B0A45

P304

Q34555024-36239072-2E81-4514-B54B-FB61D02827FF

P31

Q34555024-140A37E7-5916-401B-A7E5-E5195A7FEA74

P356

Q34555024-3B063EB0-6D5B-4654-8D83-BEC1CED8D524

P433

Q34555024-E87E2F34-B4EB-4303-A511-1F93F6B7E869

P478

Q34555024-E3D1CF2C-AD6A-4585-84DD-40EFB9004EE1

P50

Q34555024-A708D558-9F5D-4803-AFC9-92598954CAC1

P577

Q34555024-50501786-312A-4829-A8C5-6EE7824D8F97

P5875

Q34555024-B13800EF-251E-4292-8401-EFF2612B5A91

P698

Q34555024-117C4586-2E26-4DC8-83E7-5B8C8524352A

P921

Q34555024-F0D6267B-D9A0-4615-A150-18299384A82E

P356

P1433

Human Molecular Genetics

P1476

TBC1D1 is a candidate for a se ...... ion in obesity predisposition.

@en

P2093

Alexander Gutin

http://www.w3.org/2001/XMLSchema#string

Chris D Neff

http://www.w3.org/2001/XMLSchema#string

David Frank

http://www.w3.org/2001/XMLSchema#string

Deanna L Russell

http://www.w3.org/2001/XMLSchema#string

Deborah Trem

http://www.w3.org/2001/XMLSchema#string

Diana Iliev

http://www.w3.org/2001/XMLSchema#string

Donna Shattuck

http://www.w3.org/2001/XMLSchema#string

Georges C Frech

http://www.w3.org/2001/XMLSchema#string

Gongping He

http://www.w3.org/2001/XMLSchema#string

Jerry S Lanchbury

http://www.w3.org/2001/XMLSchema#string

P2860

Prevalence and Trends in Obesity Among US Adults, 1999-2000

PedCheck: a program for identification of genotype incompatibilities in linkage analysis

Obesity and insulin resistance

A haplotype map of the human genome

Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

SMART 4.0: towards genomic data integration

Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans.

Rab GTPases, intracellular traffic and disease.

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.

P304

2709-2720

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/DDL204

http://www.w3.org/2001/XMLSchema#string

P433

18

http://www.w3.org/2001/XMLSchema#string

P478

15

http://www.w3.org/2001/XMLSchema#string

P50

P577

2006-08-07T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6893008

http://www.w3.org/2001/XMLSchema#string

P698

16893906

http://www.w3.org/2001/XMLSchema#string

P921