Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
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EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated GenesMutations in CIC and FUBP1 contribute to human oligodendrogliomaATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarizationComparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascadeGeneration of novel patient-derived CIC- DUX4 sarcoma xenografts and cell lines.Lateral gene expression in Drosophila early embryos is supported by Grainyhead-mediated activation and tiers of dorsally-localized repression.A dynamic network of morphogens and transcription factors patterns the fly legPrecise developmental gene expression arises from globally stochastic transcriptional activityOrigins of context-dependent gene repression by capicua.Novel CIC point mutations and an exon-spanning, homozygous deletion identified in oligodendroglial tumors by a comprehensive genomic approach including transcriptome sequencing.Deficiency of Capicua disrupts bile acid homeostasis.BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanismsPattern formation by graded and uniform signals in the early Drosophila embryo.Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking.The Capicua repressor--a general sensor of RTK signaling in development and disease.A Systematic Ensemble Approach to Thermodynamic Modeling of Gene Expression from Sequence Data.A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.Torso RTK controls Capicua degradation by changing its subcellular localizationDynamics of Inductive ERK Signaling in the Drosophila Embryo.A system of repressor gradients spatially organizes the boundaries of Bicoid-dependent target genes.Gene regulation by MAPK substrate competition.Context-dependent transcriptional interpretation of mitogen activated protein kinase signaling in the Drosophila embryo.Kinetics of gene derepression by ERK signalingMinibrain and Wings apart control organ growth and tissue patterning through down-regulation of CapicuaSize-dependent regulation of dorsal-ventral patterning in the early Drosophila embryo.Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.Genetic regulation and function of epidermal growth factor receptor signalling in patterning of the embryonic Drosophila brain.Su(H)-mediated repression positions gene boundaries along the dorsal-ventral axis of Drosophila embryos.Co-option of a coordinate system defined by the EGFr and Dpp pathways in the evolution of a morphological noveltyUncoupling neurogenic gene networks in the Drosophila embryo.Context-dependent enhancer selection confers alternate modes of notch regulation on argos.EGFR-dependent downregulation of Capicua and the establishment of Drosophila dorsoventral polarity.COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation.A double-edged sword: The world according to Capicua in cancer.Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation.Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.Capicua controls Toll/IL-1 signaling targets independently of RTK regulation.Using CRISPR-Cas9 to Study ERK Signaling in Drosophila.Genome-wide CRISPR/Cas9 Screen Identifies Host Factors Essential for Influenza Virus Replication.The Capicua tumor suppressor: a gatekeeper of Ras signaling in development and cancer.
P2860
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P2860
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@ast
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@en
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@nl
type
label
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@ast
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@en
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@nl
prefLabel
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@ast
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@en
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@nl
P2093
P2860
P356
P1433
P1476
Capicua DNA-binding sites are general response elements for RTK signaling in Drosophila
@en
P2093
Aharon Helman
Albert J Courey
Claudia Nieva
Clint Winkler
Dennis Kuo
Leiore Ajuria
María José Andreu
Sergio González-Crespo
Ze'ev Paroush
P2860
P304
P356
10.1242/DEV.057729
P407
P577
2011-01-26T00:00:00Z