The Capicua repressor--a general sensor of RTK signaling in development and disease.
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EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated GenesEpidermal growth factor signalling controls myosin II planar polarity to orchestrate convergent extension movements during Drosophila tubulogenesisMolecular Testing of Brain Tumor.Whole-Genome Sequence of the Metastatic PC3 and LNCaP Human Prostate Cancer Cell Lines.Comparative transcriptome analysis of isogenic cell line models and primary cancers links capicua (CIC) loss to activation of the MAPK signalling cascadeGeneration of novel patient-derived CIC- DUX4 sarcoma xenografts and cell lines.A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.Identification of hidden relationships from the coupling of hydrophobic cluster analysis and domain architecture information.Origins of context-dependent gene repression by capicua.Deficiency of Capicua disrupts bile acid homeostasis.Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking.A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer.Torso RTK controls Capicua degradation by changing its subcellular localizationKnockdown of receptor tyrosine kinase-like orphan receptor 2 inhibits cell proliferation and colony formation in osteosarcoma cells by inducing arrest in cell cycle progression.miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progressionDistinct transcriptional regulatory modules underlie STAT3's cell type-independent and cell type-specific functions.Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations.Kinetics of gene derepression by ERK signalingIs glioblastoma an epigenetic malignancy?Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of CapicuaInactivation of Capicua drives cancer metastasisSmoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.ROR2 inhibits the proliferation of gastric carcinoma cells via activation of non-canonical Wnt signaling.A comparative study of Pointed and Yan expression reveals new complexity to the transcriptional networks downstream of receptor tyrosine kinase signaling.EGFR induces DNA decomposition via phosphodiester bond cleavageThe evolving molecular genetics of low-grade glioma.Capicua regulates proliferation and survival of RB-deficient cells in Drosophila.Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.The Diagnostic Use of Immunohistochemical Surrogates for Signature Molecular Genetic Alterations in Gliomas.A genetic interaction analysis identifies cancer drivers that modify EGFR dependency.CIC inactivating mutations identify aggressive subset of 1p19q codeleted gliomas.ETV transcriptional upregulation is more reliable than RNA sequencing algorithms and FISH in diagnosing round cell sarcomas with CIC gene rearrangements.CIC break-apart fluorescence in-situ hybridization misses a subset of CIC-DUX4 sarcomas: a clinicopathological and molecular study.Parallel imaging of Drosophila embryos for quantitative analysis of genetic perturbations of the Ras pathway.The equilibrium between antagonistic signaling pathways determines the number of synapses in Drosophila.ATXN1L, CIC, and ETS Transcription Factors Modulate Sensitivity to MAPK Pathway Inhibition.EGFR-dependent downregulation of Capicua and the establishment of Drosophila dorsoventral polarity.COP9 signalosome subunits protect Capicua from MAPK-dependent and -independent mechanisms of degradation.Characterization of Bbx, a member of a novel subfamily of the HMG-box superfamily together with Cic.A double-edged sword: The world according to Capicua in cancer.
P2860
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P2860
The Capicua repressor--a general sensor of RTK signaling in development and disease.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The Capicua repressor--a general sensor of RTK signaling in development and disease.
@ast
The Capicua repressor--a general sensor of RTK signaling in development and disease.
@en
type
label
The Capicua repressor--a general sensor of RTK signaling in development and disease.
@ast
The Capicua repressor--a general sensor of RTK signaling in development and disease.
@en
prefLabel
The Capicua repressor--a general sensor of RTK signaling in development and disease.
@ast
The Capicua repressor--a general sensor of RTK signaling in development and disease.
@en
P2860
P356
P1476
The Capicua repressor--a general sensor of RTK signaling in development and disease
@en
P2093
Stanislav Y Shvartsman
Ze'ev Paroush
P2860
P304
P356
10.1242/JCS.092965
P407
P577
2012-03-01T00:00:00Z