The active core in a triazole peptide dual-site antagonist of HIV-1 gp120. - Wikidata - awgldk - TriplyDB

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

http://www.wikidata.org/entity/Q34558123

about

Click chemistry in peptide-based drug design Abasic phosphorothioate oligomers inhibit HIV-1 reverse transcription and block virus transmission across polarized ectocervical organ cultures.Covalent conjugation of a peptide triazole to HIV-1 gp120 enables intramolecular binding site occupancy Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation.Antiviral breadth and combination potential of peptide triazole HIV-1 entry inhibitors.Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120.Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.HIV-1 Env gp120 structural determinants for peptide triazole dual receptor site antagonism.Peptide triazole inactivators of HIV-1: how do they work and what is their potential?Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity.A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption Non-natural peptide triazole antagonists of HIV-1 envelope gp120.HIV envelope: challenges and opportunities for development of entry inhibitors.10 years of click chemistry: synthesis and applications of ferrocene-derived triazoles.Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.Recognition of HIV-inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664.Cell-free HIV-1 virucidal action by modified peptide triazole inhibitors of Env gp120.Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions.Restricted HIV-1 Env Glycan Engagement by Lectin-Reengineered DAVEI Protein Chimera is sufficient for Lytic Inactivation of the Virus.Synthesis and antioxidant evaluation of enantiomerically pure bis-(1,2,3-triazolylmethyl)amino esters from modified α-amino acids.

P2860

Q26853053-E102DC2E-76BA-4978-A847-05AFCAC96E11 Q30366821-4FE1423B-DC46-4675-B1E7-D6BBBAC9AE15 Q33710476-7A332B0C-1A06-4B63-8194-0CF192D06443 Q33727192-1B8DD0D6-1996-47BB-B640-7671001BC03D Q34801630-2F32A59B-6F77-45EE-A1B9-BA7561D1EA88 Q35689392-E69C6123-4CF9-4D20-871B-80E6DA0228B9 Q35835515-4476A08B-CE9F-44FF-B9E6-A27E98E9571B Q36812126-1B3814B7-B0E8-4072-8B7A-B0B2E91F9B94 Q37063734-EE78190E-0427-41F0-80DC-CBE2390D9D8E Q37081209-C98015EB-EEC6-4009-BE54-557F98054273 Q37183472-30C44ABC-EEBF-40F8-B6E2-9AF49606131D Q37238636-1EFE4074-C9EA-48BD-AC2E-B43C96CB83A9 Q37260033-8CC3C89C-4E8E-4237-9DDC-72E617A57346 Q37850183-8E7CE461-41F0-464C-8097-507C04282ED3 Q37924709-751C9445-4F0B-4A8F-A679-FC63ABC402D9 Q38647724-32ECA405-4104-4E2B-B513-906C76D992D5 Q38774504-2DBA8EBB-DF71-448F-8B01-E6DD2980A294 Q39516140-EE18AA46-E1CE-4AA5-945E-DD033211CFD0 Q41846910-3957F326-2A82-4143-9884-5952785CBF3D Q47552223-690FB493-C71B-4A2A-B309-F99FAA1A4442 Q55621301-C5A3A450-5CD1-42B9-AACB-CB71E0DAA051

P2860

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

http://www.wikidata.org/entity/Q34558123

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@ast

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@en

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@nl

type

label

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@ast

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@en

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@nl

prefLabel

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@ast

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@en

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@nl

P1433

Q34558123-90ADF233-D0E9-4629-BCA2-AF830BC22E90

P1476

Q34558123-EA331071-94F0-4B20-A52D-A55566D3BBC3

P2093

Q34558123-045EF25E-5F16-4CC6-A126-5A84A1BF6753

Q34558123-1F3808DD-6268-4670-ADDD-BD3E2B174194

Q34558123-3F6959A1-88B0-4AED-BD46-789C9FBFFF21

Q34558123-49C3A782-FEBD-4948-9A14-D0478FBDD4AC

Q34558123-6FEC56F9-2CA7-4923-BFF6-D244E702BF68

Q34558123-754904F6-9E86-4C41-BE13-996F2F5F0433

Q34558123-8212E5FC-FEC9-4B69-B58D-D98F32F37044

Q34558123-C06B5685-6415-4BD6-9480-4CEB7B30821B

Q34558123-C13D9F2C-9906-4CB3-80D1-F2535FEE0A09

Q34558123-E19DB02B-7882-41F1-B7E3-6CC284B8D39A

P2860

Q34558123-04D63B79-23C2-4138-B9F8-E9122F9616C5

Q34558123-07F3AD57-A8A2-4422-8F46-FE0D991D37C9

Q34558123-1021C8B5-9231-42D2-AE1F-074A944614C4

Q34558123-35030AF7-EA07-488B-A657-7E3E24F5B6BE

Q34558123-3A52CB1B-F958-46EE-8482-9AE779BF6114

Q34558123-4028CA6A-C8B7-4547-A9E2-6B04015D9B7C

Q34558123-437338B7-9F46-4184-9087-FF6A83165AED

Q34558123-4B1BE587-AFDA-4809-8FFF-63B25AC435B5

Q34558123-594EE709-BABC-47D9-A2D2-664F41AA371B

Q34558123-5A2AA186-B995-4A09-AA54-496D8974235D

P304

Q34558123-00A186AD-549D-4FD0-83D1-150914DAF5F0

P31

Q34558123-F9F66017-1D30-47E0-840A-37251D0C509A

P356

Q34558123-2CBA8E8C-C079-4D20-9492-A83B0A55027E

P433

Q34558123-1A99FF3F-FEB2-47EB-A232-64E576EA5C54

P478

Q34558123-542167BD-CE1E-428E-A2C7-5CA35A96B785

P577

Q34558123-13565AED-068A-4039-A46C-DE353FC30EBD

P5875

Q34558123-415DC827-D002-4630-85C4-18BD27380029

P698

Q34558123-9C659F0A-7853-47BA-B724-944438ED5B81

P932

Q34558123-998004FC-4AE1-4694-A475-EEF2F2AB4703

P356

P1433

P1476

The active core in a triazole peptide dual-site antagonist of HIV-1 gp120.

@en

P2093

Arne Schön

http://www.w3.org/2001/XMLSchema#string

Ernesto Freire

http://www.w3.org/2001/XMLSchema#string

Ferit Tuzer

http://www.w3.org/2001/XMLSchema#string

Irwin Chaiken

http://www.w3.org/2001/XMLSchema#string

Isaac Zentner

http://www.w3.org/2001/XMLSchema#string

Judith Lalonde

http://www.w3.org/2001/XMLSchema#string

Karyn McFadden

http://www.w3.org/2001/XMLSchema#string

Mark Contarino

http://www.w3.org/2001/XMLSchema#string

Muddegowda Umashankara

http://www.w3.org/2001/XMLSchema#string

Srivats Rajagopal

http://www.w3.org/2001/XMLSchema#string

P2860

Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS)

Identification of a major co-receptor for primary isolates of HIV-1

Core structure of gp41 from the HIV envelope glycoprotein

Atomic structure of the ectodomain from HIV-1 gp41

Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

Peptide ligands to human immunodeficiency virus type 1 gp120 identified from phage display libraries

Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1

P304

1871-1879

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/CMDC.201000222

http://www.w3.org/2001/XMLSchema#string

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P577

2010-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45442169

http://www.w3.org/2001/XMLSchema#string

P698

20677318

http://www.w3.org/2001/XMLSchema#string

P932

3035117

http://www.w3.org/2001/XMLSchema#string