An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects
about
Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitusAlternatively spliced variants of the insulin receptor protein. Expression in normal and diabetic human tissuesAnalysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitusSevere obesity: evidence for a deranged metabolic program in skeletal muscle?Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humansAltered expression of muscle glucose transporter GLUT-4 in diabetic fatty Zucker rats (ZDF/Drt-fa)Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patientsContraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscleCellular mechanisms of insulin resistanceEffects of diet-induced obesity on protein expression in insulin signaling pathways of skeletal muscle in male Wistar rats.Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle.Toll-like receptor 4 modulates skeletal muscle substrate metabolismAstragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation.Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitusRegulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus.Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment.Role of plasma membrane transporters in muscle metabolism.Acetyl-l-carnitine inhibits TNF-alpha-induced insulin resistance via AMPK pathway in rat skeletal muscle cells.Transmembrane glucose transport in skeletal muscle of patients with non-insulin-dependent diabetes.Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humansAngiotensin II increases glucose utilization during acute hyperinsulinemia via a hemodynamic mechanism.Reduced capacity and affinity of skeletal muscle for insulin-mediated glucose uptake in noninsulin-dependent diabetic subjects. Effects of insulin therapyInsulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance.Effects of altered glucose homeostasis on glucose transporter expression in skeletal muscle of the ratDecreased in vivo glucose uptake but normal expression of GLUT1 and GLUT4 in skeletal muscle of diabetic rats.Intracellular mechanisms underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle.Multi-omic integrated networks connect DNA methylation and miRNA with skeletal muscle plasticity to chronic exercise in Type 2 diabetic obesity.GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle.Is there a metabolic program in the skeletal muscle of obese individuals?Regulation of glucose transport in human skeletal muscle.Blood flow and muscle metabolism: a focus on insulin action.Regulation of human insulin receptor RNA splicing in vivo.Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasisSelective insulin resistance in adipocytesCausal drift, robust signaling, and complex disease.Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects.Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity.
P2860
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P2860
An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects
description
1988 nî lūn-bûn
@nan
1988 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@ast
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@en
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@nl
type
label
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@ast
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@en
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@nl
prefLabel
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@ast
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@en
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@nl
P2093
P2860
P921
P356
P1476
An in vitro human muscle prepa ...... ly obese and diabetic subjects
@en
P2093
D Meelheim
E B Tapscott
E G Flickinger
S M Atkinson
W J Pories
P2860
P304
P356
10.1172/JCI113622
P407
P577
1988-08-01T00:00:00Z