Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole.
about
Illuminating Targets of Bacterial SecretionIdentification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screeningStudying Coxiella burnetii Type IV Substrates in the Yeast Saccharomyces cerevisiae: Focus on Subcellular Localization and Protein AggregationThe Type IV Secretion System Effector Protein CirA Stimulates the GTPase Activity of RhoA and Is Required for Virulence in a Mouse Model of Coxiella burnetii InfectionEssential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells.Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes.Multiple Substrate Usage of Coxiella burnetii to Feed a Bipartite Metabolic Network.Endocytosis of viruses and bacteria.Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetiiIdentification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway.Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication.A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesisGeneration and multi-phenotypic high-content screening of Coxiella burnetii transposon mutantsYersinia pestis Requires Host Rab1b for Survival in Macrophages.Major differential gene regulation in Coxiella burnetii between in vivo and in vitro cultivation modelsCoxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCKDot/Icm Effector Translocation by Legionella longbeachae Creates a Replicative Vacuole Similar to That of Legionella pneumophila despite Translocation of Distinct Effector Repertoires.The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetiiRobust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophagesBiogenesis of the lysosome-derived vacuole containing Coxiella burnetii.Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse MacrophagesEffector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.Coxiella burnetii effector CvpB modulates phosphoinositide metabolism for optimal vacuole development.Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In VitroVinculin and Rab5 complex is required [correction of requited]for uptake of Staphylococcus aureus and interleukin-6 expressionThe SCID Mouse Model for Identifying Virulence Determinants in Coxiella burnetii.High-Content Imaging Reveals Expansion of the Endosomal Compartment during Coxiella burnetii Parasitophorous Vacuole MaturationElevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic.Hijacking of Membrane Contact Sites by Intracellular Bacterial Pathogens.A Rab-centric perspective of bacterial pathogen-occupied vacuoles.A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection.Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L.Right on Q: genetics begin to unravel Coxiella burnetii host cell interactions.The contribution of genomics to the study of Q fever.Applying Fluorescence Resonance Energy Transfer (FRET) to Examine Effector Translocation Efficiency by Coxiella burnetii during siRNA Silencing.Identification of Coxiella burnetii surface-exposed and cell envelope associated proteins using a combined bioinformatics plus proteomics strategy.DNA Delivery and Genomic Integration into Mammalian Target Cells through Type IV A and B Secretion Systems of Human Pathogens.Measuring pH of the Coxiella burnetii Parasitophorous Vacuole.Altering lipid droplet homeostasis affects Coxiella burnetii intracellular growth.
P2860
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P2860
Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole.
description
2013 nî lūn-bûn
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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
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2013年論文
@zh-mo
2013年論文
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2013年论文
@wuu
name
Effector protein translocation ...... the pathogen-occupied vacuole.
@ast
Effector protein translocation ...... the pathogen-occupied vacuole.
@en
Effector protein translocation ...... the pathogen-occupied vacuole.
@nl
type
label
Effector protein translocation ...... the pathogen-occupied vacuole.
@ast
Effector protein translocation ...... the pathogen-occupied vacuole.
@en
Effector protein translocation ...... the pathogen-occupied vacuole.
@nl
prefLabel
Effector protein translocation ...... the pathogen-occupied vacuole.
@ast
Effector protein translocation ...... the pathogen-occupied vacuole.
@en
Effector protein translocation ...... the pathogen-occupied vacuole.
@nl
P2860
P1433
P1476
Effector protein translocation ...... the pathogen-occupied vacuole.
@en
P2093
Justin A McDonough
P2860
P304
P356
10.1371/JOURNAL.PONE.0054566
P407
P577
2013-01-17T00:00:00Z