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Sel1 repeat protein LpnE is a Legionella pneumophila virulence determinant that influences vacuolar traffickingAnalysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease.The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.Two novel point mutations in clinical Staphylococcus aureus reduce linezolid susceptibility and switch on the stringent response to promote persistent infection.Molecular pathogenesis of infections caused by Legionella pneumophilaLegionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins.The Dot/Icm effector SdhA is necessary for virulence of Legionella pneumophila in Galleria mellonella and A/J miceIdentification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entryEffector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole.Molecular Detection of Legionella: Moving on From mip.A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesisDot/Icm Effector Translocation by Legionella longbeachae Creates a Replicative Vacuole Similar to That of Legionella pneumophila despite Translocation of Distinct Effector Repertoires.Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.Contribution of long polar fimbriae to the virulence of rabbit-specific enteropathogenic Escherichia coliEnzymatic properties of an ecto-nucleoside triphosphate diphosphohydrolase from Legionella pneumophila: substrate specificity and requirement for virulence.Significant role for ladC in initiation of Legionella pneumophila infection.Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.Murine Alveolar Macrophages Are Highly Susceptible to Replication of Coxiella burnetii Phase II In VitroErratum for Kohler et al., Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing VacuolePost-modern pathogens: surprising activities of translocated effectors from E. coli and Legionella.A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection.Multiple ecto-nucleoside triphosphate diphosphohydrolases facilitate intracellular replication of Legionella pneumophila.The Legionella pneumophila F-box protein Lpp2082 (AnkB) modulates ubiquitination of the host protein parvin B and promotes intracellular replication.A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila.Dot/Icm-translocated proteins important for biogenesis of the Coxiella burnetii-containing vacuole identified by screening of an effector mutant sub-library.Interaction between autophagic vesicles and the Coxiella-containing vacuole requires CLTC (clathrin heavy chain)Coxiella burnetii utilizes both glutamate and glucose during infection with glucose uptake mediated by multiple transportersLysosomal degradation products induce Coxiella burnetii virulenceEirA is a novel protein essential for intracellular replication of Coxiella burnetiiThe multifunctional enzyme S-adenosylhomocysteine/methylthioadenosine nucleosidase is a key metabolic enzyme in the virulence of Salmonella enterica var TyphimuriumLoss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional RegulatorsBiogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3Taming the Triskelion: Bacterial Manipulation of ClathrinSopF, a phosphoinositide binding effector, promotes the stability of the nascent Salmonella-containing vacuoleSdrA, an NADP(H)-regenerating enzyme, is crucial for Coxiella burnetii to resist oxidative stress and replicate intracellularly
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Hayley J Newton
@nl
Hayley J Newton
@sl
Hayley J. Newton
@en
Hayley J. Newton
@es
type
label
Hayley J Newton
@nl
Hayley J Newton
@sl
Hayley J. Newton
@en
Hayley J. Newton
@es
prefLabel
Hayley J Newton
@nl
Hayley J Newton
@sl
Hayley J. Newton
@en
Hayley J. Newton
@es
P106
P1153
7007174117
P2798
P31
P496
0000-0002-9240-2001