Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity.
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HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypassHydroxymethylglutaryl-CoA reductase inhibitors (statins) for the treatment of sepsisHMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypassConservation between human and fungal squalene synthetases: similarities in structure, function, and regulationMevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agentLovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductaseCholesterol feedback: from Schoenheimer's bottle to Scap's MELADLHMG-CoA reductase inhibition aborts functional differentiation and triggers apoptosis in cultured primary human monocytes: a potential mechanism of statin-mediated vasculoprotectionNatural Products to Counteract the Epidemic of Cardiovascular and Metabolic DisordersHigh Cholesterol Deteriorates Bone Health: New Insights into Molecular MechanismsSaccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductaseA century of cholesterol and coronaries: from plaques to genes to statinsA novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitroThematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part V: the discovery of the statins and the end of the controversyThe gamma subunit of transducin is farnesylatedNeutrophils are required for the DNA synthetic response of human lymphocytes to mevalonic acid: evidence suggesting that a nonsterol product of mevalonate is involvedDifferential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sitesStatin Use and Risk of Cirrhosis and Related Complications in Patients with Chronic Liver Diseases: a Systematic Review and Meta-analysis.Racial Differences in the Cholesterol-Lowering Effect of Statin.Future translational applications from the contemporary genomics era: a scientific statement from the American Heart AssociationImportance of microbial natural products and the need to revitalize their discovery.Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statinsSuppression of statin effectiveness by copper and zinc in yeast and human cellsA historical perspective on the discovery of statins.Essential role for mevalonate synthesis in DNA replication.Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductaseEnzymes of the mevalonate pathway of isoprenoid biosynthesisPharmacotherapy of hypercholesterolaemia: statins in clinical practice.In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.Lipids and atherosclerosis: clinical management of hypercholesterolaemia.Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins.Pitavastatin approved for treatment of primary hypercholesterolemia and combined dyslipidemia.Effect of simvastatin and fenofibrate on the fatty acid composition of hypercholesterolaemic patientsColorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene.A chemical genomic study identifying diversity in cell migration signaling in cancer cells.Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestineSuppression of murine neuroblastoma growth in vivo by mevinolin, a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductaseHypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia.Cell cycle regulation of metallothionein in human colonic cancer cells.Jeremiah Metzger Lecture: cholesterol, inflammation and atherosclerotic cardiovascular disease: is it all LDL?
P2860
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P2860
Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity.
description
1976 nî lūn-bûn
@nan
1976 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1976 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1976年の論文
@ja
1976年論文
@yue
1976年論文
@zh-hant
1976年論文
@zh-hk
1976年論文
@zh-mo
1976年論文
@zh-tw
1976年论文
@wuu
name
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@ast
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@en
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@nl
type
label
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@ast
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@en
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@nl
prefLabel
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@ast
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@en
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@nl
P2093
P1433
P1476
Competitive inhibition of 3-hy ...... hypocholesterolemic activity.
@en
P2093
P304
P356
10.1016/0014-5793(76)80996-9
P407
P577
1976-12-01T00:00:00Z