X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM.
about
Solution structure of the complex of VEK-30 and plasminogen kringle 2Crystal Structure of Prothrombin Reveals Conformational Flexibility and Mechanism of ActivationCrystal structure of the native plasminogen reveals an activation-resistant compact conformationEffects on human plasminogen conformation and activation rate caused by interaction with VEK-30, a peptide derived from the group A streptococcal M-like protein (PAM).Dimerization is not a determining factor for functional high affinity human plasminogen binding by the group A streptococcal virulence factor PAM and is mediated by specific residues within the PAM a1a2 domain.Pathogen activators of plasminogenA natural inactivating mutation in the CovS component of the CovRS regulatory operon in a pattern D Streptococcal pyogenes strain influences virulence-associated genesPlasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain.
P2860
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P2860
X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@ast
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@en
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@nl
type
label
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@ast
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@en
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@nl
prefLabel
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@ast
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@en
X-ray crystallographic structu ...... ptococcal surface protein PAM.
@nl
P2093
P356
P1433
P1476
X-ray crystallographic structu ...... eptococcal surface protein PAM
@en
P2093
Francis J Castellino
Mary Prorok
Sara E Cnudde
P304
11052-11060
P356
10.1021/BI060914J
P407
P577
2006-09-01T00:00:00Z