Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.

Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.

Item
http://www.wikidata.org/entity/Q37339330
Residues essential for plasminogen binding by the cation-independent mannose 6-phosphate receptorSkizzle is a novel plasminogen- and plasmin-binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generationEngineering streptokinase for generation of active site-labeled plasminogen analogs.Pathogen activators of plasminogenFull time course kinetics of the streptokinase-plasminogen activation pathway.Small-molecule modulators of zymogen activation in the fibrinolytic and coagulation systems.Molecular processes in the streptokinase thrombolytic therapy.Sequence and kinetic analyses of streptokinase from two group G streptococci with high fibrin-dependent plasminogen activities and the identification of novel altered amino acids as potential hot spots.Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation.Identification through combinatorial random and rational mutagenesis of a substrate-interacting exosite in the gamma domain of streptokinase.Pitfalls in screening streptococci for retrieving superior streptokinase (SK) genes: no activity correlation for streptococcal culture supernatant and recombinant SK.
P2860

Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and kringle 5 of the substrate.

Item
http://www.wikidata.org/entity/Q37339330
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 27 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Plasminogen substrate recognit ...... nd kringle 5 of the substrate.
@en
Plasminogen substrate recognit ...... nd kringle 5 of the substrate.
@nl
type
label
Plasminogen substrate recognit ...... nd kringle 5 of the substrate.
@en
Plasminogen substrate recognit ...... nd kringle 5 of the substrate.
@nl
prefLabel
Plasminogen substrate recognit ...... nd kringle 5 of the substrate.
@en
Plasminogen substrate recognit ...... nd kringle 5 of the substrate.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Plasminogen substrate recognit ...... and kringle 5 of the substrate
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932