Methylated arsenicals: the implications of metabolism and carcinogenicity studies in rodents to human risk assessment. - Wikidata - awgldk - TriplyDB

Methylated arsenicals: the implications of metabolism and carcinogenicity studies in rodents to human risk assessment.

Methylated arsenicals: the implications of metabolism and carcinogenicity studies in rodents to human risk assessment.

http://www.wikidata.org/entity/Q34567906

about

Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium Nutritional manipulation of one-carbon metabolism: effects on arsenic methylation and toxicity Arsenic Toxicity in Male Reproduction and Development Arsenic exposure and toxicology: a historical perspective Arsenic, asbestos and radon: emerging players in lung tumorigenesis Contribution of breast milk and formula to arsenic exposure during the first year of life in a US prospective cohort Effects of arsenic exposure on DNA methylation and epigenetic gene regulation Low-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cells Drosophotoxicology: the growing potential for Drosophila in neurotoxicology Metabolism, toxicity and anticancer activities of arsenic compounds.Immunotoxicity and biodistribution analysis of arsenic trioxide in C57Bl/6 mice following a 2-week inhalation exposure Evaluation of the carcinogenicity of gallium arsenide.Evaluation of the carcinogenicity of inorganic arsenic.Draft Genome Sequence of Nitrincola sp. Strain A-D6, an Arsenic-Resistant Gammaproteobacterium Isolated from a Salt Flat.A broad view of arsenic.Rice consumption contributes to arsenic exposure in US women.Folic acid supplementation lowers blood arsenic Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H mice.Tissue dosimetry, metabolism and excretion of pentavalent and trivalent dimethylated arsenic in mice after oral administration.Transcriptional Modulation of the ERK1/2 MAPK and NF-κB Pathways in Human Urothelial Cells After Trivalent Arsenical Exposure: Implications for Urinary Bladder Cancer.Dual actions involved in arsenite-induced oxidative DNA damage.Good outcomes despite high urinary arsenic concentrations from overdose with crabgrass killer.In vitro toxicological characterization of two arsenosugars and their metabolites.Arsenic-based antineoplastic drugs and their mechanisms of action.Oral exposure to inorganic arsenic: evaluation of its carcinogenic and non-carcinogenic effects.Arsenic: toxicity, oxidative stress and human disease.Arsenic geochemistry of groundwater in Southeast Asia.Arsenic metabolism and thioarsenicals.Speciated arsenic in air: measurement methodology and risk assessment considerations.Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review.The evolving use of arsenic in pharmacotherapy of malignant disease.Cardiovascular effects of arsenic: clinical and epidemiological findings.New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis.Diuron-induced rat urinary bladder carcinogenesis: mode of action and human relevance evaluations using the International Programme on Chemical Safety framework.A review of metal-catalyzed molecular damage: protection by melatonin.The use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.Agent Orange exposure and risk of death in Korean Vietnam veterans: Korean Veterans Health Study.Redox- and non-redox-metal-induced formation of free radicals and their role in human disease.SILAC-based quantitative proteomic analysis reveals widespread molecular alterations in human skin keratinocytes upon chronic arsenic exposure.

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P2860

Methylated arsenicals: the implications of metabolism and carcinogenicity studies in rodents to human risk assessment.

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Lora L Arnold

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P2860

Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals

Arsenic and urinary bladder cell proliferation

Oxidative DNA adducts and DNA-protein cross-links are the major DNA lesions induced by arsenite

Association of chromosomal alterations with arsenite-induced tumorigenicity of human HaCaT keratinocytes in nude mice.

Arsenic-induced enhancement of ultraviolet radiation carcinogenesis in mouse skin: a dose-response study

The role of biomethylation in toxicity and carcinogenicity of arsenic: a research update.

Arsenic enhancement of skin neoplasia by chronic stimulation of growth factors

Enzymatic methylation of arsenic compounds. VII. Monomethylarsonous acid (MMAIII) is the substrate for MMA methyltransferase of rabbit liver and human hepatocytes

Enzymatic reduction of arsenic compounds in mammalian systems: the rate-limiting enzyme of rabbit liver arsenic biotransformation is MMA(V) reductase

Elucidating the pathway for arsenic methylation

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