Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations. - Wikidata - awgldk - TriplyDB

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

http://www.wikidata.org/entity/Q34568313

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Strategies for Pharmacological Organoprotection during Extracorporeal Circulation Targeting Ischemia-Reperfusion Injury Profile of minocycline and its potential in the treatment of schizophrenia Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy Single-wall carbon nanohorns inhibited activation of microglia induced by lipopolysaccharide through blocking of Sirt3 A data-driven approach for evaluating multi-modal therapy in traumatic brain injury.Inhibitors of cytochrome c release with therapeutic potential for Huntington's disease Poly(ADP-ribose) polymerase-1 and its cleavage products differentially modulate cellular protection through NF-kappaB-dependent signaling A novel target of action of minocycline in NGF-induced neurite outgrowth in PC12 cells: translation initiation [corrected] factor eIF4AI.Sex differences in minocycline-induced neuroprotection after experimental stroke Anti-inflammatory Actions of Adjunctive Tetracyclines and Other Agents in Periodontitis and Associated Comorbidities.Targeting microglial activation in stroke therapy: pharmacological tools and gender effects.NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death Vincristine attenuates N-methyl-N'-nitro-N-nitrosoguanidine-induced poly-(ADP) ribose polymerase activity in cardiomyocytes.Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture.A 2 × 2 factorial design for the combination therapy of minocycline and remote ischemic perconditioning: efficacy in a preclinical trial in murine thromboembolic stroke model Inputs and outputs of poly(ADP-ribosyl)ation: Relevance to oxidative stress Evidence for neuroinflammatory and microglial changes in the cerebral response to sleep loss.Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo.Minocycline protects cardiac myocytes against simulated ischemia–reperfusion injury by inhibiting poly(ADP-ribose) polymerase-1.Peripheral nerve pathology, including aberrant Schwann cell differentiation, is ameliorated by doxycycline in a laminin-α2-deficient mouse model of congenital muscular dystrophy.Prospects for minocycline neuroprotection.Sexual dimorphism in ischemic stroke: lessons from the laboratory.Effects of minocycline on learning and memory of mice following ischemic-hypoxic cerebral injuries Minocycline development for acute ischemic stroke Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines Minocycline-induced attenuation of iron overload and brain injury after experimental intracerebral hemorrhage Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.Pharmacological inhibition of poly(ADP-ribose) polymerase inhibits angiogenesis Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke.Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor.The mitochondrial death pathway: a promising therapeutic target in diseases Minocycline inhibits peritoneal macrophages but activates alveolar macrophages in acute pancreatitis.Novel modulators of poly(ADP-ribose) polymerase.Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocycline Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly(ADP-ribose) polymerase PARP inhibitors and heart failure--translational medicine caught in the act.Minocycline: far beyond an antibiotic.A pilot open-label trial of minocycline in patients with autism and regressive features A novel non-antibacterial, non-chelating hydroxypyrazoline derivative of minocycline inhibits nociception and oedema in mice.

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P2860

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

http://www.wikidata.org/entity/Q34568313

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006 թվականի հունիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Minocycline inhibits poly

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

@ast

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

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type

label

Minocycline inhibits poly

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

@en

prefLabel

Minocycline inhibits poly

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

@ast

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

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Proceedings of the National Academy of Sciences of the United States of America

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Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations

@en

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Andreu Viader Valls

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Conrad C Alano

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Raymond A Swanson

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P2860

Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death

Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria

Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease.

Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

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103

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Tiina M. Kauppinen

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