Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1. - Wikidata - awgldk - TriplyDB

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

http://www.wikidata.org/entity/Q34568861

about

Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability Recent progress toward epigenetic therapies: the example of mixed lineage leukemia Epigenetics in Cancer: A Hematological Perspective Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate.The oncoprotein EVI1 and the DNA methyltransferase Dnmt3 co-operate in binding and de novo methylation of target DNA.Reproducibility and concordance of differential DNA methylation and gene expression in cancer.High DNA methyltransferase DNMT3B levels: a poor prognostic marker in acute myeloid leukemia.Association between DNA methyltransferases 3B gene polymorphisms and the susceptibility to acute myeloid leukemia in Chinese Han population.Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy Method to detect differentially methylated loci with case-control designs using Illumina arrays.Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia.EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.Identification of differentially methylated markers among cytogenetic risk groups of acute myeloid leukemia Mutations in DNA methyltransferase (DNMT3A) observed in acute myeloid leukemia patients disrupt processive methylation Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia A noncanonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia.Overexpression of Evi-1 oncoprotein represses TGF-β signaling in colorectal cancer.Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes.Minimal residual disease testing to predict relapse following transplant for AML and high-grade myelodysplastic syndromes.Evi1 forms a bridge between the epigenetic machinery and signaling pathways.PRDM proteins: important players in differentiation and disease.Prognostic implications of genetic aberrations in acute myelogenous leukemia with normal cytogenetics.Epigenetic regulation of miRNA genes in acute leukemia.Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis.DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences.Origins of aberrant DNA methylation in acute myeloid leukemia.Chromatin modifiers and the promise of epigenetic therapy in acute leukemia The use of molecular genetics to refine prognosis in acute myeloid leukemia.Induction of the proapoptotic tumor suppressor gene Cell Adhesion Molecule 1 by chemotherapeutic agents is repressed in therapy resistant acute myeloid leukemia.A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression.BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemia.EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells.Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.Pediatric chronic myeloid leukemia with inv(3)(q21q26.2) and T lymphoblastic transformation: a case report.Monitoring Response and Resistance to the Novel Arsenical Darinaparsin in an AML Patient.Aberrant expression of ecotropic viral integration site-1 in acute myeloid leukemia and acute lymphoblastic leukemia.DNMT3a methylation in neuropathic pain.miRNA-22 is a Novel Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation and Neointima Formation.

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Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

http://www.wikidata.org/entity/Q34568861

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@ast

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@en

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

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type

label

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@ast

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@en

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@nl

prefLabel

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@ast

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

@en

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

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Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1.

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Ari Melnick

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Claudia Erpelinck-Verschueren

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Eric Bindels

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Lucy Skrabanek

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Maria E Figueroa

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Yushan Li

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Bioconductor: open software development for computational biology and bioinformatics

TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins

Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer

BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

DAVID: Database for Annotation, Visualization, and Integrated Discovery

The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase

Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor

The epigenomics of cancer

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