DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences. - Wikidata - awgldk - TriplyDB

DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences.

DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences.

http://www.wikidata.org/entity/Q38040883

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Core Binding Factor Acute Myeloid Leukemia: New Prognostic Categories and Therapeutic Opportunities Epigenetic silencing of Kruppel like factor-3 increases expression of pro-metastatic miR-182.Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis.Cellular determinants for preclinical activity of a novel CD33/CD3 bispecific T-cell engager (BiTE) antibody, AMG 330, against human AML.Casticin inhibits the activity of transcription factor Sp1 and the methylation of RECK in MGC803 gastric cancer cells.Conventional chemotherapy or hypomethylating agents for older patients with acute myeloid leukaemia?Alternative novel therapies for the treatment of elderly acute myeloid leukemia patients.DNA methylation regulated gene expression in organ fibrosis.Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival.

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DNA methyltransferase inhibitors in acute myeloid leukemia: discovery, design and first therapeutic experiences.

http://www.wikidata.org/entity/Q38040883

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DNA methyltransferase inhibito ...... first therapeutic experiences.

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DNA methyltransferase inhibito ...... first therapeutic experiences.

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DNA methyltransferase inhibito ...... first therapeutic experiences.

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17460441.2012.722618

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Expert Opinion on Drug Discovery

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DNA methyltransferase inhibito ...... first therapeutic experiences.

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Xavier Thomas

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

The Polycomb group protein EZH2 directly controls DNA methylation

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Tumour class prediction and discovery by microarray-based DNA methylation analysis

Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

DNMT3A Mutations in Acute Myeloid Leukemia

Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.

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1039-1051

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10.1517/17460441.2012.722618

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2012-09-05T00:00:00Z

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22950862

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