Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
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Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivityPrimary erythromelalgia: a reviewStructure-based assessment of disease-related mutations in human voltage-gated sodium channels.Mutations at opposite ends of the DIII/S4-S5 linker of sodium channel Na V 1.7 produce distinct pain disordersA novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgia.A novel SCN9A mutation responsible for primary erythromelalgia and is resistant to the treatment of sodium channel blockersMutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders.Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype.Novel SCN9A mutations underlying extreme pain phenotypes: unexpected electrophysiological and clinical phenotype correlations.Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels.Network topology of NaV1.7 mutations in sodium channel-related painful disorders.Mutation I136V alters electrophysiological properties of the Na(v)1.7 channel in a family with onset of erythromelalgia in the second decadeCompound heterozygosity in sodium channel Nav1.7 in a family with hereditary erythermalgiaBlocking sodium channels to treat neuropathic pain.Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitableVoltage-gated sodium channel blockers for the treatment of neuropathic pain.Modulation of human Nav1.7 channel gating by synthetic α-scorpion toxin OD1 and its analogs.Visualizing sodium dynamics in isolated cardiomyocytes using fluorescent nanosensorsSodium channel blockers for the treatment of neuropathic pain.Severe case and literature review of primary erythromelalgia: novel SCN9A gene mutation.Genetic aspects of sodium channelopathy in small fiber neuropathy.A new Nav1.7 sodium channel mutation I234T in a child with severe pain.Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability.A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.Biophysical properties of human Na v1.7 splice variants and their regulation by protein kinase A.Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel.Early- and late-onset inherited erythromelalgia: genotype-phenotype correlation.Inherited erythromelalgia due to mutations in SCN9A: natural history, clinical phenotype and somatosensory profile.Mutations in Sodium Channel Gene SCN9A and the Pain Perception Disorders
P2860
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P2860
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
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2006 nî lūn-bûn
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2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
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2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@ast
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@en
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
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Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@ast
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@en
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@nl
prefLabel
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@ast
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@en
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@nl
P2093
P2860
P356
P1476
Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating.
@en
P2093
Angelika Lampert
Lynda Tyrrell
Stephen G Waxman
Sulayman D Dib-Hajj
P2860
P304
36029-36035
P356
10.1074/JBC.M607637200
P407
P577
2006-09-28T00:00:00Z