An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.
about
Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipidsCholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case studyOrganophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoidsSelectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profilingThe pharmacological landscape and therapeutic potential of serine hydrolasesFunctional Proteomic and Structural Insights into Molecular Recognition in the Nitrilase Family Enzymes † ‡Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticidesNew members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activityReconstruction of biochemical networks in microorganismsActivity-Based Protein Profiling of Oncogene-Driven Changes in Metabolism Reveals Broad Dysregulation of PAFAH1B2 and 1B3 in Cancer.Activity-based proteomic and metabolomic approaches for understanding metabolismChemoproteomic discovery of AADACL1 as a regulator of human platelet activation.Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.Oxime esters as selective, covalent inhibitors of the serine hydrolase retinoblastoma-binding protein 9 (RBBP9).Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence.Finding enzymes that are actively involved in cancer.RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia.Exposure Marker Discovery of Phthalates Using Mass Spectrometry.Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screeningInositol phosphate recycling regulates glycolytic and lipid metabolism that drives cancer aggressiveness.Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis.Metabolic profiling reveals PAFAH1B3 as a critical driver of breast cancer pathogenicity.Metabolomic strategies to map functions of metabolic pathwaysActivation of the endocannabinoid system by organophosphorus nerve agents.Discovery libraries targeting the major enzyme classes: the serine hydrolases.How chemoproteomics can enable drug discovery and developmentExploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platformsAbsence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophagesXCMS Online: a web-based platform to process untargeted metabolomic data.Metabolomic strategies for the identification of new enzyme functions and metabolic pathwaysChemical proteomics and its impact on the drug discovery process.Chemistry-based functional proteomics for drug target deconvolution.Simultaneous extraction and rapid visualization of peptidomic and lipidomic body fluids fingerprints using mesoporous aluminosilicate and MALDI-TOF MS.Activity-based protein profiling for biochemical pathway discovery in cancer.Target deconvolution techniques in modern phenotypic profiling.Metastasis: new perspectives on an old problemChemical genetics screening reveals KIAA1363 as a cytokine-lowering target.Activity-based protein profiling of organophosphorus and thiocarbamate pesticides reveals multiple serine hydrolase targets in mouse brain
P2860
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P2860
An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
An enzyme that regulates ether ...... by multidimensional profiling.
@ast
An enzyme that regulates ether ...... by multidimensional profiling.
@en
An enzyme that regulates ether ...... by multidimensional profiling.
@nl
type
label
An enzyme that regulates ether ...... by multidimensional profiling.
@ast
An enzyme that regulates ether ...... by multidimensional profiling.
@en
An enzyme that regulates ether ...... by multidimensional profiling.
@nl
prefLabel
An enzyme that regulates ether ...... by multidimensional profiling.
@ast
An enzyme that regulates ether ...... by multidimensional profiling.
@en
An enzyme that regulates ether ...... by multidimensional profiling.
@nl
P2093
P1476
An enzyme that regulates ether ...... by multidimensional profiling.
@en
P2093
Alan Saghatelian
Kyle P Chiang
Sherry Niessen
P304
P356
10.1016/J.CHEMBIOL.2006.08.008
P577
2006-10-01T00:00:00Z