Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition - Wikidata - awgldk - TriplyDB

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

http://www.wikidata.org/entity/Q34577381

about

Chronic over-nutrition and dysregulation of GSK3 in diseases Cell Death Conversion under Hypoxic Condition in Tumor Development and Therapy Natural product-based nanomedicine: recent advances and issues A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death Advanced glycation endproducts trigger autophagy in cadiomyocyte via RAGE/PI3K/AKT/mTOR pathway Leucine signaling in the pathogenesis of type 2 diabetes and obesity PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.Apigenin-induced lysosomal degradation of β-catenin in Wnt/β-catenin signaling.Matrine induces Akt/mTOR signalling inhibition-mediated autophagy and apoptosis in acute myeloid leukaemia cells.Human bocavirus induces apoptosis and autophagy in human bronchial epithelial cells.Suppression of tumor growth by Pleurotus ferulae ethanol extract through induction of cell apoptosis, and inhibition of cell proliferation and migration.Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy.Autophagy-regulating small molecules and their therapeutic applications.Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation Consumption of coffee associated with reduced risk of liver cancer: a meta-analysis Isogambogenic acid induces apoptosis-independent autophagic cell death in human non-small-cell lung carcinoma cells Collaboration of geldanamycin-activated P70S6K and Hsp70 against beta-amyloid-induced hippocampal apoptosis: an approach to long-term memory and learning Caffeine mediates sustained inactivation of breast cancer-associated myofibroblasts via up-regulation of tumor suppressor genes.Combination of Cl‑IB‑MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR‑dependent autophagy and mitotic catastrophe on human melanoma cells.Apoptosis, autophagy, necroptosis, and cancer metastasis P150glued-associated disorders are caused by activation of intrinsic apoptotic pathway Conophylline protects cells in cellular models of neurodegenerative diseases by inducing mammalian target of rapamycin (mTOR)-independent autophagy.P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells.Effect of pollen typhae on inhibiting autophagy in spinal cord injury of rats and its mechanisms Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2.Platycodin-D Induced Autophagy in Non-Small Cell Lung Cancer Cells via PI3K/Akt/mTOR and MAPK Signaling Pathways.Protective Effect of Sevoflurane Postconditioning against Cardiac Ischemia/Reperfusion Injury via Ameliorating Mitochondrial Impairment, Oxidative Stress and Rescuing Autophagic Clearance.Inhibition of Autophagy Potentiated the Antitumor Effect of Nedaplatin in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway.PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway.Arachidonic acid enhances caffeine-induced cell death via caspase-independent cell death.JNK-Bcl-2/Bcl-xL-Bax/Bak Pathway Mediates the Crosstalk between Matrine-Induced Autophagy and Apoptosis via Interplay with Beclin 1.Coffee provides a natural multitarget pharmacopeia against the hallmarks of cancer.Antagonism between curcumin and the topoisomerase II inhibitor etoposide: a study of DNA damage, cell cycle regulation and death pathways.Porcine circovirus type 2 induces autophagy via the AMPK/ERK/TSC2/mTOR signaling pathway in PK-15 cells Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity.

P2860

Q26738964-523489EB-30D9-46D9-A8D4-A426EC0FB7C1 Q26778008-AFE43089-08AA-49C0-AF34-91E3F8457F3E Q26785633-59903275-FB31-47AA-8561-1DC6D746E570 Q26849503-27D64FB5-F28F-4829-B4F9-FA4FC4C32DAF Q28385402-E627BD39-F617-4726-BDA6-538225D83907 Q28391784-E6546D8A-B753-40B3-B867-E22CDDADE335 Q28566602-393FF569-B009-409E-940F-84E62A46A226 Q29543116-C33F13EE-1AC8-46B8-86B1-11D1A386CE90 Q30090238-A6CA382B-54B7-420C-885C-4F4E5427C21A Q33672053-CF771EA2-794F-405A-8D33-731F4A2AFFEB Q33684337-D75AAB07-14C9-4EFA-B030-69B86AC1A35B Q33847360-49544807-AE5F-4982-94F3-5EB441DD5B23 Q33910820-BBF731DF-253D-4BA2-A9DF-B35587400EDE Q34022661-1348C7FB-A59E-4FF5-8DE4-A0D006F4F759 Q34147157-EA92B3D5-1B15-4911-98D0-5322B022D582 Q34516761-BA9F62E0-645C-4EBD-8EFF-BFE75D7FDEA4 Q34596852-CBB00C71-61F0-43E1-B2B9-51221B7D1E3D Q34877847-5EC13B9E-1910-45ED-A69B-369CF0402061 Q35078844-4E617025-E1B8-413E-9E60-52075B00BE89 Q35111214-19D4A544-7F03-4B48-9D56-1CF978B5445C Q35128510-53F53963-F9BA-45E0-95C2-C1737910CC61 Q35128650-28C0B3E0-0A90-44F7-B3CD-F2D182E2AA02 Q35145435-EBD595EC-8E8A-4026-BB85-F336666503FF Q35172924-C2D8C9D8-D216-40E1-93C9-F6FBB549CBFC Q35176143-8CB70041-DC97-4EB4-8327-75E174BD2575 Q35604137-A8F2EC0C-A011-462F-9609-E00A4679AD87 Q35632010-993B119B-1317-406E-BFC5-68582081F91D Q35644250-71CFDD71-D2DF-46BD-8AB6-3B8F8EF7C030 Q35739530-B2617F21-3023-4E27-88B2-000678745234 Q35742639-CCCF1466-0030-4B8D-8F04-A63D642B4E47 Q35750358-8E1C895F-0907-4728-92BC-653910656558 Q35798939-854D9117-4D6A-4553-A4C9-9345828F4375 Q35832384-99F4E27C-B13E-443C-9C5C-4262910A043A Q36022303-0932F96C-4BD3-4AA2-BA84-B2A280FB40FD Q36164982-668F8B21-761E-4545-975B-5DD03DFB8ECB Q36247594-9ED02B25-3D9D-4C77-BB8E-65155C176AA5 Q36289486-F9E7C858-8466-4A17-A8A9-F651D86B95A5 Q36289907-15B689F4-359D-4BAF-BAF7-0C4E0F3A2E0D Q36363788-7E89164F-7DAE-464B-9932-6B5B39D3FAA0 Q36557120-61FBA643-BEFA-4A71-9DE9-0C4E7994CF7B

P2860

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

http://www.wikidata.org/entity/Q34577381

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@ast

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@en

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@nl

type

label

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@ast

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@en

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@nl

prefLabel

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@ast

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@en

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@nl

P1433

Q34577381-726E5D4B-ACB5-4B51-8F26-9CB94E72466C

P1476

Q34577381-E40B77FB-0FD1-448A-AA33-07F53728F4E1

P2093

Q34577381-1EA40949-0A18-4137-A601-5A9382AFE8CE

Q34577381-52492BD5-48FB-4BAC-A6BB-F8EF01823AE8

Q34577381-9C499A9D-3CA6-43DF-A329-3DA59923AB20

Q34577381-A2017625-F7FD-4B9A-BB27-6B34B968081B

Q34577381-A63645B4-EFD0-45D2-B89C-0565CDE058FD

Q34577381-A726FA4A-E5A1-41E9-A774-93018ED65FF0

Q34577381-CDD32B4C-2C56-485E-9268-159843F768A8

Q34577381-CE6DD335-A816-4E97-B3EC-820F0D16D292

Q34577381-CFD5BAE8-E742-494C-B815-F38888C4574E

Q34577381-D620F645-B367-4C4E-93AA-640D79858CF8

P2860

Q34577381-01D9765A-434F-4F81-9807-0FDCA34CA9AA

Q34577381-0890807E-A985-437C-B945-B1A51A998917

Q34577381-13E11247-4756-4FF2-A8A5-3EAD2EC2DE10

Q34577381-2096D7CB-7E42-42C8-BAC1-61023ECF6D61

Q34577381-20E7AB8B-48C0-4A44-82AE-A112FE2E7D77

Q34577381-216629B0-E587-4442-8E45-374D3FFFAF93

Q34577381-257A68AD-C2B5-4338-A6AC-2C6EC62835F2

Q34577381-396BE7DA-B14F-4A2F-9317-9F724564E0DB

Q34577381-3ABD5E94-2B25-4A12-9B83-518206977EF4

Q34577381-3D34DFFD-C3F4-40B3-B2AA-BEC7AFC11D73

P304

Q34577381-C705D2E9-D7C4-403D-BDA3-6DFE99B165E6

P31

Q34577381-9A47631E-634A-4E05-964D-AE0D05FF784F

P356

Q34577381-811DC85B-8BB8-45C3-800B-AE4DB118584D

P433

Q34577381-869BE51C-D1A8-4EA7-B3DB-CD3B2B7CC43A

P478

Q34577381-80551708-1AF2-4D04-8BC4-C94AD1871DAD

P50

Q34577381-5198B787-AED6-4D27-8BE0-C60DF573D125

P577

Q34577381-B2E91520-0EE8-4B10-84FA-7BD2B2FD4385

P5875

Q34577381-9F1B5B25-8A98-4AF6-A85C-21DEACE35165

P698

Q34577381-3F90DB35-BE8F-46F2-A741-6228DC99BEBF

P921

Q34577381-3D762B44-FDE4-4FAC-8C0E-69E529E7A01A

P932

Q34577381-961202E7-B033-4486-9283-A2BB0F3CD92B

P356

P1433

P1476

Caffeine induces apoptosis by ...... I3K/Akt/mTOR/p70S6K inhibition

@en

P2093

Fumiaki Sato

http://www.w3.org/2001/XMLSchema#string

Hiroki Kobayashi

http://www.w3.org/2001/XMLSchema#string

Isei Tanida

http://www.w3.org/2001/XMLSchema#string

Ken-Ichi Ishikawa

http://www.w3.org/2001/XMLSchema#string

Masaya Imoto

http://www.w3.org/2001/XMLSchema#string

Shigeto Sato

http://www.w3.org/2001/XMLSchema#string

Shinji Saiki

http://www.w3.org/2001/XMLSchema#string

Sumihiro Kawajiri

http://www.w3.org/2001/XMLSchema#string

Takahiro Fujimaki

http://www.w3.org/2001/XMLSchema#string

Yoko Imamichi

http://www.w3.org/2001/XMLSchema#string

P2860

The Hallmarks of Cancer

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes

Autophagy fights disease through cellular self-digestion

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

The roles of intracellular protein-degradation pathways in neurodegeneration

P304

176-187

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4161/AUTO.7.2.14074

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

7

http://www.w3.org/2001/XMLSchema#string

P50

Nobutaka Hattori

P577

2011-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

47809335

http://www.w3.org/2001/XMLSchema#string

P698

21081844

http://www.w3.org/2001/XMLSchema#string

P921

P932

3039768

http://www.w3.org/2001/XMLSchema#string