PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2 - Wikidata - awgldk - TriplyDB

PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

http://www.wikidata.org/entity/Q34577769

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miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice Regulation of KAT6 Acetyltransferases and Their Roles in Cell Cycle Progression, Stem Cell Maintenance, and Human Disease The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis A phase I trial of the aurora kinase inhibitor, ENMD-2076, in patients with relapsed or refractory acute myeloid leukemia or chronic myelomonocytic leukemia.Stem cells' guided gene therapy of cancer: New frontier in personalized and targeted therapy.The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ-TIF2 fusion.Essential role of PU.1 in maintenance of mixed lineage leukemia-associated leukemic stem cells.Vascularity of nongynecological leiomyosarcoma depends on colony-stimulating factor 1 but not on vascular endothelial growth factor.PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway.Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia.PU.1 affects proliferation of the human acute myeloid leukemia U937 cell line by directly regulating MEIS1.Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells TGF-β1-induced transcription factor networks in Langerhans cell development and maintenance.Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes.Genomic and biochemical insights into the specificity of ETS transcription factors.TIM-3 as a therapeutic target for malignant stem cells in acute myelogenous leukemia.Complexity of cancer stem cells.The MYSTerious MOZ, a histone acetyltransferase with a key role in haematopoiesis.Stem cell maintenance and disease progression in chronic myeloid leukemia.TIM-3 as a novel therapeutic target for eradicating acute myelogenous leukemia stem cells.Emerging therapeutic targets in human acute myeloid leukemia (part 2) - bromodomain inhibition should be considered as a possible strategy for various patient subsets.The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia.Hematopoietic stem/progenitor cell differentiation towards myeloid lineage is modulated by LIGHT/LIGHT receptor signaling.Upregulation of CD200R1 in lineage-negative leukemic cells is characteristic of AML1-ETO-positive leukemia in mice.Expression of the MOZ-TIF2 oncoprotein in mice represses senescence Colony Stimulating Factor-1 Receptor Expressing Cells Infiltrating the Cornea Control Corneal Nerve Degeneration in Response to HSV-1 Infection.CSF-1 receptor signalling is governed by pre-requisite EHD1 mediated receptor display on the macrophage cell surface Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment.Senescence is a Spi1-induced anti-proliferative mechanism in primary hematopoietic cells.Transcriptional and Microenvironmental Regulation of Lineage Ambiguity in Leukemia.Acetylation and deacetylation in cancer stem-like cells.Histone Acetyltransferase KAT6A Upregulates PI3K/AKT Signaling through TRIM24 Binding.

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PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

http://www.wikidata.org/entity/Q34577769

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2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Nature Medicine

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E Richard Stanley

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Etsuro Ito

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Harinder Singh

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Hiroaki Ohno

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Issay Kitabayashi

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Kiminori Terui

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Pu Zhang

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Takuo Katsumoto

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Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

Stem cells, cancer, and cancer stem cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

A c-fms tyrosine kinase inhibitor, Ki20227, suppresses osteoclast differentiation and osteolytic bone destruction in a bone metastasis model

MOZ is essential for maintenance of hematopoietic stem cells

Monocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cells

Plat-E: an efficient and stable system for transient packaging of retroviruses

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.

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10.1038/NM.2122

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5

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20418886

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