The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy.
about
Trpm4 differentially regulates Th1 and Th2 function by altering calcium signaling and NFAT localizationLower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseHow much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientationStructural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c-I-ET-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex InteractionsIMPIPS: the immune protection-inducing protein structure concept in the search for steric-electron and topochemical principles for complete fully-protective chemically synthesised vaccine developmentHigh-affinity T cell receptor differentiates cognate peptide-MHC and altered peptide ligands with distinct kinetics and thermodynamics.Rational design of T cell receptors with enhanced sensitivity for antigen.Rebalancing immune specificity and function in cancer by T-cell receptor gene therapy.T cell avidity and tumor immunity: problems and solutionsDiversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and functionQuantum chemical calculations predict biological function: the case of T cell receptor interaction with a peptide/MHC class I.Why do adaptive immune responses cross-react?Polyspecificity of T cell and B cell receptor recognition.Specificity of T-cell alloreactivity.Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies.Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity.T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity.TCR transgenes and transgene cassettes for TCR gene therapy: status in 2008.Different strategies adopted by K(b) and L(d) to generate T cell specificity directed against their respective bound peptides.The two-faced T cell epitope: examining the host-microbe interface with JanusMatrix.Molecular immunology lessons from therapeutic T-cell receptor gene transfer.Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragmentsAlloreactive T cells respond specifically to multiple distinct peptide-MHC complexes.Cytomegalovirus-Specific CD8+ T-Cells With Different T-Cell Receptor Affinities Segregate T-Cell Phenotypes and Correlate With Chronic Graft-Versus-Host Disease in Patients Post-Hematopoietic Stem Cell Transplantation.
P2860
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P2860
The study of high-affinity TCRs reveals duality in T cell recognition of antigen: specificity and degeneracy.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The study of high-affinity TCR ...... n: specificity and degeneracy.
@ast
The study of high-affinity TCR ...... n: specificity and degeneracy.
@en
The study of high-affinity TCR ...... n: specificity and degeneracy.
@nl
type
label
The study of high-affinity TCR ...... n: specificity and degeneracy.
@ast
The study of high-affinity TCR ...... n: specificity and degeneracy.
@en
The study of high-affinity TCR ...... n: specificity and degeneracy.
@nl
prefLabel
The study of high-affinity TCR ...... n: specificity and degeneracy.
@ast
The study of high-affinity TCR ...... n: specificity and degeneracy.
@en
The study of high-affinity TCR ...... n: specificity and degeneracy.
@nl
P2093
P1476
The study of high-affinity TCR ...... en: specificity and degeneracy
@en
P2093
David L Donermeyer
David M Kranz
Paul M Allen
P304
P356
10.4049/JIMMUNOL.177.10.6911
P407
P50
P577
2006-11-01T00:00:00Z