NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth - Wikidata - awgldk - TriplyDB

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

http://www.wikidata.org/entity/Q34582832

about

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers Direct inhibition of the NOTCH transcription factor complex Cancer systems biology: a network modeling perspective Aberrant Wnt Signaling in Leukemia Cancer Stem Cell Hierarchy in Glioblastoma Multiforme Role of Notch signaling in regulating innate immunity and inflammation in health and disease Notch signaling: its roles and therapeutic potential in hematological malignancies Regulation of Bim in Health and Disease MYC, Metabolism, and Cancer SGF29 and Sry pathway in hepatocarcinogenesis What a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathway Targeting the Notch signaling pathway in cancer therapeutics Redefining ALL classification: toward detecting high-risk ALL and implementing precision medicine From fly wings to targeted cancer therapies: a centennial for notch signaling The "virgin birth", polyploidy, and the origin of cancer Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation.The relevance of PTEN-AKT in relation to NOTCH1-directed treatment strategies in T-cell acute lymphoblastic leukemia Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signaling Sustained proliferation in cancer: Mechanisms and novel therapeutic targets Notch3 is dispensable for thymocyte β-selection and Notch1-induced T cell leukemogenesis Presenilins regulate alphabeta T cell development by modulating TCR signaling Proliferation and osteogenic differentiation of mesenchymal stem cells induced by a short isoform of NELL-1 Analysis of mammalian gene batteries reveals both stable ancestral cores and highly dynamic regulatory sequences Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia MYC on the path to cancer Richter transformation of CLL.Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma.Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia.MYLK and MYL9 expression in non-small cell lung cancer identified by bioinformatics analysis of public expression data.A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).Theory and limitations of genetic network inference from microarray data.Structural and functional insights into the human Börjeson-Forssman-Lehmann syndrome-associated protein PHF6.Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes.Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.NOTCH is part of the transcriptional network regulating cell growth and survival in mouse plasmacytomas The transcriptional network for mesenchymal transformation of brain tumours.Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling

P2860

Q24296476-65D450AB-1A50-4E99-80BB-9F79AA82774E Q24301606-40BFB4C3-9A35-4E33-A39B-3A6E4F6F7A34 Q24318306-64316D3F-BA7D-4718-8AF8-34D9619C7090 Q24634015-290849F1-9149-4DDE-9D2D-50D50F3577B2 Q24650086-C5090FF4-6E4D-4E82-838B-532916D56052 Q26738411-5F298AAB-AC3D-4F24-9E9E-0BCF519A41EC Q26752312-8CB8E763-0713-45BF-81FF-3EB6D40B0694 Q26764946-8E7405DE-5E26-4D3E-AFD1-1A6CAC33AF83 Q26765033-2201CF01-C6C8-4EA3-9329-AA90EA504E95 Q26781203-C931F1FE-1B9E-435C-92EC-5F531446487D Q26783555-A64DC3C9-A166-465F-BDDC-850AF3BCF679 Q26795760-EF760F1E-1932-49FB-8094-781A9AD75802 Q26825780-762915A9-926A-4CC1-B397-03B0B5E31639 Q26863580-C3758592-315C-4440-9E15-3516823B6085 Q26864460-2D44C5AB-8C50-4F82-831F-FBC6B9FA8A89 Q27004534-5DED3F91-0F50-4CAB-BF63-4B282E5351BC Q27024916-65E2FB6C-B822-4456-BA27-478D3DCAD0C2 Q27329779-E6E9373B-7B1A-4BD2-BD0A-054226454E25 Q27851655-1E48ADDC-8D60-4001-8A35-DE337D5F895B Q28075211-EB421AC7-2C9C-4956-8418-6544ED8D2BDE Q28118040-089CF3C8-6078-4603-A9D6-D9A94496AABC Q28396388-95BA1819-18F9-4473-9956-A244AC8500FE Q28477072-5FA2EB26-E444-4487-9E64-5AEE65545132 Q28587555-2C5DA850-BA9B-4C20-B916-505877F21026 Q28648379-3A3AE966-CC32-4D1E-8A68-40ABB10A8AB7 Q28755362-7E088C40-2291-4296-BD90-59DECD5B798B Q29614659-8C71E3F2-44A3-404C-B140-DE7D1288D192 Q29619979-6C87D26F-B8A0-4FAE-9580-700D26119EFB Q30249283-816235C6-FA44-49DF-9665-264D373AD949 Q30406012-5755E6B9-7F61-4E39-B19E-F5A1AEEF1ACD Q30537596-76A04D2A-9DC8-4B75-8CCD-432B964B9FB6 Q30847076-32672DDE-4A73-4D27-8B9E-2AD9B078EBB2 Q31016573-D88A7E50-0173-4152-9E04-7A1FA266EF6C Q31132642-C81D2BF5-D8CE-477B-92EF-73C57292F9B3 Q31814788-DC64A8E4-467B-4B06-A507-DB203DB31A90 Q33494549-DD8944C3-678D-4EAA-AC91-62B96AB65FAA Q33531734-445731A1-D304-4B83-8892-25C2526CF806 Q33567153-93ABE243-D959-4F27-9F11-272D4B8D8709 Q33572162-A251AA6D-4BBD-4C79-AD63-37250B1E743B Q33608508-6348A196-9C48-4A4B-861C-8F55606E0293

P2860

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

http://www.wikidata.org/entity/Q34582832

description

2006 nî lūn-bûn

@nan

2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@ast

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@en

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@nl

type

label

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@ast

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@en

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@nl

prefLabel

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@ast

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@en

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@nl

P1433

Q34582832-EFB1E495-9D9F-4AD0-90DB-5844E334687C

P1476

Q34582832-C0F50198-2802-488A-8966-5D30113A3C2E

P2093

Q34582832-0DBCA675-D80A-4B6C-994F-210DCD22DDAD

Q34582832-166E6183-F205-4FEE-99ED-0008F7FD13AA

Q34582832-50FDB68D-A651-46B3-92DA-B879305898AE

Q34582832-5C17808B-B40E-4723-8E46-79057384E33E

Q34582832-7424C4C3-DA83-48DA-B26B-CC681EE3789F

Q34582832-87926F79-34DA-451C-99E8-522A409C6176

Q34582832-8A68BC11-1511-41C5-8303-F5BEB276FE3D

Q34582832-8AEC6396-E237-441F-9FEF-0AFCFC230F00

Q34582832-951C1A4C-7022-42B9-8024-98BE6B6B57F6

Q34582832-AE280BBA-72DE-40E9-9394-7F5CA3F344F3

P2860

Q34582832-054F60CC-ECF4-4FED-BA7F-A460F5A8A79D

Q34582832-28BFEA46-343C-49C1-B533-5A4F109AB09F

Q34582832-2E23BDB3-1700-4527-A6DA-24AA76A92968

Q34582832-3378D290-0D79-4676-BDF0-AA3D09AB886E

Q34582832-4E102C09-083D-4E9F-BE59-EA08CF3469F2

Q34582832-527D969B-D624-4D0A-AF62-933544EF6B2B

Q34582832-546B27F5-448B-43C9-BAD4-9DA0D8118592

Q34582832-58A976DD-049B-4A63-B32C-DAAA453A19A7

Q34582832-638D871B-D66A-4BE3-8006-A5B4C9AC41B3

Q34582832-6FC9E55B-2282-4ED9-B646-EEECCF3D9CEB

P304

Q34582832-E6DE0A5D-B258-4F78-8C98-19321DCD901D

P31

Q34582832-E5C39576-F91C-4FCA-9D75-DE5428E39BD3

P356

Q34582832-0DFF6739-A261-464B-809D-E565A0CA7F04

P407

Q34582832-899FB67F-87C3-4ED3-B082-0EE2863EF920

P433

Q34582832-86DBDAFD-E2F6-4E77-A908-F5AAEE573B71

P478

Q34582832-C8FCF1B5-C09D-4E3D-A09B-EC34E74F8476

P50

Q34582832-1A55B3F2-102C-4957-BF8E-53BDA198E2DC

Q34582832-414F8546-5CBB-4E76-8A30-CFD52CD326C4

Q34582832-D3B92D92-6DAF-4F28-879B-D1ED3DD5BC64

P577

Q34582832-1FD488C6-F9E6-4CC0-974F-7ED985CCE987

P5875

Q34582832-E7C0C636-07AD-4676-8B7F-4E640DBA0B0A

P698

Q34582832-476A88DC-7BF2-4C49-8089-86E58DAE7D44

P921

Q34582832-02DAABFD-DFC4-4212-A07B-5AED446F9212

P932

Q34582832-CE900AA1-7B1B-4E6C-9ABF-F0A7AAC65918

P356

PNAS.0606108103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

NOTCH1 directly regulates c-MY ...... promoting leukemic cell growth

@en

P2093

A Thomas Look

http://www.w3.org/2001/XMLSchema#string

Adam Margolin

http://www.w3.org/2001/XMLSchema#string

Adolfo A Ferrando

http://www.w3.org/2001/XMLSchema#string

Andrea Califano

http://www.w3.org/2001/XMLSchema#string

Andrew P Weng

http://www.w3.org/2001/XMLSchema#string

Donna Neuberg

http://www.w3.org/2001/XMLSchema#string

Francois Sigaux

http://www.w3.org/2001/XMLSchema#string

Jean Soulier

http://www.w3.org/2001/XMLSchema#string

Jennifer O'Neil

http://www.w3.org/2001/XMLSchema#string

Jon C Aster

http://www.w3.org/2001/XMLSchema#string

P2860

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila

Control of pancreas and liver gene expression by HNF transcription factors

DAVID: Database for Annotation, Visualization, and Integrated Discovery

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen

Reverse engineering of regulatory networks in human B cells

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.

P304

18261-18266

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.0606108103

http://www.w3.org/2001/XMLSchema#string

P407

P433

48

http://www.w3.org/2001/XMLSchema#string

P478

103

http://www.w3.org/2001/XMLSchema#string

P50

P577

2006-11-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6684158

http://www.w3.org/2001/XMLSchema#string

P698

17114293

http://www.w3.org/2001/XMLSchema#string

P921

P932

1838740

http://www.w3.org/2001/XMLSchema#string