Novel antisense and peptide nucleic acid strategies for controlling gene expression.
about
Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.Pseudocomplementary PNAs as selective modifiers of protein activity on duplex DNA: the case of type IIs restriction enzymesKnockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo.Biochemical prevention and treatment of viral infections - a new paradigm in medicine for infectious diseasesEnd invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes.Synthetic genomics and synthetic biology applications between hopes and concernsStructural studies on LNA quadruplexes.Enhanced cellular uptake of a triplex-forming oligonucleotide by nanoparticle formation in the presence of polypropylenimine dendrimersThe application of RAGE and GECKO in cell-based target discovery screens.High-content imaging analysis of the knockdown effects of validated siRNAs and antisense oligonucleotides.Chemical modification: the key to clinical application of RNA interference?siRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model.Regulation of oxidative stress response by CosR, an essential response regulator in Campylobacter jejuni.Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera designThe potential of antisense as a CNS therapeutic.Pyrrolidinyl peptide nucleic acid with α/β-peptide backbone: A conformationally constrained PNA with unusual hybridization propertiesPurification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage.Gene delivery approaches to heart failure treatment.(α,α-dimethyl)glycyl (dmg) PNAs: achiral PNA analogs that form stronger hybrids with cDNA relative to isosequential RNA.A versatile method for the preparation of conjugates of peptides with DNA/PNA/analog by employing chemo-selective click reaction in water.Telomerase inhibition in cancer therapeutics: molecular-based approachesActivator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.New peptide nucleic acid analogues: synthesis and applications.Effective delivery of antisense peptide nucleic acid oligomers into cells by anthrax protective antigenHairpin ribozyme-antisense RNA constructs can act as molecular Lassos.2'-O-methyl-modified phosphorothioate antisense oligonucleotides have reduced non-specific effects in vitro.Phosphorothioate nucleotides and oligonucleotides - recent progress in synthesis and application.Nanostructure-induced DNA condensation.Purification and assembly of thermostable Cy5 labeled γ-PNAs into a 3D DNA nanocage.2'-fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity.GNA/aegPNA chimera loaded with RNA binding preference.Polyamine derivatives as selective RNaseA mimicsInhibition of transcription by bisPNA-peptide conjugates.RNA bandages for photoregulating in vitro protein synthesis.Antisense Oligonucleotide-Based Therapy for Neuromuscular Disease.Molecular self-assembly using peptide nucleic acids.In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides.Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA.Tailoring the activity of restriction endonuclease PleI by PNA-induced DNA looping.Delivery of antisense peptide nucleic acids (PNAs) to the cytosol by disulphide conjugation to a lipophilic cation.
P2860
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P2860
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@ast
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@en
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@nl
type
label
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@ast
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@en
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@nl
prefLabel
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@ast
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@en
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@nl
P356
P1433
P1476
Novel antisense and peptide nucleic acid strategies for controlling gene expression.
@en
P2093
David R Corey
Dwaine A Braasch
P304
P356
10.1021/BI0122112
P407
P577
2002-04-01T00:00:00Z