Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study - Wikidata - awgldk - TriplyDB

Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study

Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study

http://www.wikidata.org/entity/Q34586428

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MUC4 is negatively regulated through the Wnt/β-catenin pathway via the Notch effector Hath1 in colorectal cancer.Subversion of human intestinal mucosa innate immunity by a Crohn's disease-associated E. coli.

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P2860

Differential roles of Hath1, MUC2 and P27Kip1 in relation with gamma-secretase inhibition in human colonic carcinomas: a translational study

http://www.wikidata.org/entity/Q34586428

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2013 nî lūn-bûn

@nan

2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Differential roles of Hath1, M ...... cinomas: a translational study

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Differential roles of Hath1, M ...... cinomas: a translational study

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Differential roles of Hath1, M ...... cinomas: a translational study

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type

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Differential roles of Hath1, M ...... cinomas: a translational study

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Differential roles of Hath1, M ...... cinomas: a translational study

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Differential roles of Hath1, M ...... cinomas: a translational study

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prefLabel

Differential roles of Hath1, M ...... cinomas: a translational study

@ast

Differential roles of Hath1, M ...... cinomas: a translational study

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Differential roles of Hath1, M ...... cinomas: a translational study

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JOURNAL.PONE.0055904

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Differential roles of Hath1, M ...... cinomas: a translational study

@en

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Béatrice Charreau

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Chantal Bou-Hanna

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Christian L Laboisse

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Christine Kandel

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François Leclair

http://www.w3.org/2001/XMLSchema#string

Frédérique Souazé

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Jean-François Mosnier

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Julie Devallière

http://www.w3.org/2001/XMLSchema#string

Stéphane Bézieau

http://www.w3.org/2001/XMLSchema#string

P2860

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

Signalling downstream of activated mammalian Notch

Atonal homolog 1 is a tumor suppressor gene

Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

Colorectal cancer in mice genetically deficient in the mucin Muc2

Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

Notch2 signaling sensitizes endothelial cells to apoptosis by negatively regulating the key protective molecule survivin.

Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis.

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e55904

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scholarly article

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10.1371/JOURNAL.PONE.0055904

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2

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Stéphane Bézieau

Chantal Bou-Hanna

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2013-02-11T00:00:00Z

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235622093

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23409082

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3569436

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