Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration
about
DMSO and betaine greatly improve amplification of GC-rich constructs in de novo synthesis.Expression of Ciona intestinalis AOX causes male reproductive defects in Drosophila melanogasterMitochondrial ROS production correlates with, but does not directly regulate lifespan in DrosophilaExpression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.Therapies in inborn errors of oxidative metabolism.Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproductionGenetic mosaic analysis of a deleterious mitochondrial DNA mutation in Drosophila reveals novel aspects of mitochondrial regulation and function.Mitochondrial energetics and therapeutics.Diiron centre mutations in Ciona intestinalis alternative oxidase abolish enzymatic activity and prevent rescue of cytochrome oxidase deficiency in fliesGene therapy of the other genome: the challenges of treating mitochondrial DNA defects.Restoration of electron transport without proton pumping in mammalian mitochondria.Progress and prospects: gene therapy for mitochondrial DNA disease.Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency.Engineering the alternative oxidase gene to better understand and counteract mitochondrial defects: state of the art and perspectives.The approaches for manipulating mitochondrial proteomeMitochondrial medicine: to a new era of gene therapy for mitochondrial DNA mutations.Emerging aspects of treatment in mitochondrial disorders.Expression of the alternative oxidase complements cytochrome c oxidase deficiency in human cells.Glucose modulates respiratory complex I activity in response to acute mitochondrial dysfunction.Heterologous expression of the Crassostrea gigas (Pacific oyster) alternative oxidase in the yeast Saccharomyces cerevisiae.Functional expression of plant alternative oxidase decreases antimycin A-induced reactive oxygen species production in human cells.Mitochondria are physiologically maintained at close to 50 °C.Engineering plant alternative oxidase function in mammalian cells: substitution of the motif-like sequence ENV for QDT diminishes catalytic activity of Arum concinnatum AOX1a expressed in HeLa cells.An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations.Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidaseMitochondrial Supercomplexes Do Not Enhance Catalysis by Quinone Channeling
P2860
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P2860
Allotopic expression of a mitochondrial alternative oxidase confers cyanide resistance to human cell respiration
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Allotopic expression of a mito ...... ance to human cell respiration
@ast
Allotopic expression of a mito ...... ance to human cell respiration
@en
Allotopic expression of a mito ...... ance to human cell respiration
@nl
type
label
Allotopic expression of a mito ...... ance to human cell respiration
@ast
Allotopic expression of a mito ...... ance to human cell respiration
@en
Allotopic expression of a mito ...... ance to human cell respiration
@nl
prefLabel
Allotopic expression of a mito ...... ance to human cell respiration
@ast
Allotopic expression of a mito ...... ance to human cell respiration
@en
Allotopic expression of a mito ...... ance to human cell respiration
@nl
P2093
P2860
P356
P1433
P1476
Allotopic expression of a mito ...... ance to human cell respiration
@en
P2093
Emmanuel P Dassa
Gerrit A J Hakkaart
Howard T Jacobs
Pierre Rustin
P2860
P304
P356
10.1038/SJ.EMBOR.7400601
P577
2005-12-02T00:00:00Z