Progress and prospects: gene therapy for mitochondrial DNA disease.
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Mitochondrial geneticsDeveloping a genetic approach to investigate the mechanism of mitochondrial competence for DNA importGene delivery to mitochondria by targeting modified adenoassociated virus suppresses Leber's hereditary optic neuropathy in a mouse model.Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.The neuro-ophthalmology of mitochondrial diseaseDual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery.A protein shuttle system to target RNA into mitochondria.Transfection of plant mitochondria and in organello gene integration.Correcting human mitochondrial mutations with targeted RNA import.Nuclear expression of a mitochondrial DNA gene: mitochondrial targeting of allotopically expressed mutant ATP6 in transgenic mice.Mutant NADH dehydrogenase subunit 4 gene delivery to mitochondria by targeting sequence-modified adeno-associated virus induces visual loss and optic atrophy in miceManipulation of mtDNA heteroplasmy in all striated muscles of newborn mice by AAV9-mediated delivery of a mitochondria-targeted restriction endonuclease.Emerging therapies for mitochondrial disorders.Mitochondrial medicine: to a new era of gene therapy for mitochondrial DNA mutations.Strength training as a countermeasure to aging muscle and chronic disease.Treatment of hereditary optic neuropathies.Mitochondrial dysfunction in central nervous system white matter disorders.Assessing the Delivery of Molecules to the Mitochondrial Matrix Using Click ChemistryDNA delivery to mitochondria: sequence specificity and energy enhancement.Trial and error: how the unclonable human mitochondrial genome was cloned in yeast.Acceptance and Access to Gene Editing: Science and Our Obligations to Mankind.Mitochondrial versus nuclear gene expression and membrane protein assembly: The case of subunit 2 of yeast cytochrome c oxidase.
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Progress and prospects: gene therapy for mitochondrial DNA disease.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Progress and prospects: gene therapy for mitochondrial DNA disease.
@en
Progress and prospects: gene therapy for mitochondrial DNA disease.
@nl
type
label
Progress and prospects: gene therapy for mitochondrial DNA disease.
@en
Progress and prospects: gene therapy for mitochondrial DNA disease.
@nl
prefLabel
Progress and prospects: gene therapy for mitochondrial DNA disease.
@en
Progress and prospects: gene therapy for mitochondrial DNA disease.
@nl
P2093
P2860
P921
P356
P1433
P1476
Progress and prospects: gene therapy for mitochondrial DNA disease.
@en
P2093
D S Kyriakouli
R N Lightowlers
R W Taylor
P2860
P2888
P304
P356
10.1038/GT.2008.91
P577
2008-05-22T00:00:00Z