Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human
about
Improved retroviral vectors for gene transfer and expression.An alternative approach to somatic cell gene therapy.Overcoming interference to retroviral superinfection results in amplified expression and transmission of cloned genes.Efficient transduction by an amphotropic retrovirus vector is dependent on high-level expression of the cell surface virus receptorSelection of transduced CD34+ progenitors and enzymatic correction of cells from Gaucher patients, with bicistronic vectorsDesign of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans.p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation.DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectorsHelper-free foamy virus vectorsAdeno-associated virus vectors preferentially transduce cells in S phase.Adenosine deaminase gene expression is regulated posttranscriptionally in the nucleusDevelopment of 2A peptide-based strategies in the design of multicistronic vectors.Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes.Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex.Retrovirus-mediated transfer of an adenovirus gene encoding an integral membrane protein is sufficient to down regulate the receptor for epidermal growth factor.Cutaneous gene therapy.Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy.Recombinant retroviruses encoding cell surface antigens as selectable markers.Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region.Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes.Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells.Drug delivery by genetically engineered cell implants.Long-term transplantation of canine keratinocytes made resistant to G418 through retrovirus-mediated gene transfer.Restoration of normal lysosomal function in mucopolysaccharidosis type VII cells by retroviral vector-mediated gene transfer.Gene therapy: current status and future directions.Retroviral vectors: from cancer viruses to therapeutic toolsGene therapy for genetic diseases.Different mechanisms account for the relative resistance of KG-1 and HL-60 cell lines to retrovirus infection.Isolation and analysis of different subpopulations of normal human breast epithelial cells after their infection with a retroviral vector encoding a cell surface marker.Restoration of arylsulphatase B activity in human mucopolysaccharidosis-type-VI fibroblasts by retroviral-vector-mediated gene transfer.Sustained gene expression in transplanted skin fibroblasts in rats.How realistic is cutaneous gene therapy?Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: implications for gene therapy.
P2860
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P2860
Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human
description
1987 nî lūn-bûn
@nan
1987 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1987 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
name
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@ast
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@en
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@nl
type
label
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@ast
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@en
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@nl
prefLabel
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@ast
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@en
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@nl
P2093
P2860
P356
P1476
Efficient retrovirus-mediated ...... sine deaminase-deficient human
@en
P2093
A D Miller
T D Palmer
W R Osborne
P2860
P304
P356
10.1073/PNAS.84.4.1055
P407
P577
1987-02-01T00:00:00Z