Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes.
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Correction of mucopolysaccharidosis type IIIb fibroblasts by lentiviral vector-mediated gene transferMultiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skinStable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAsGene therapy in clinical medicineA murine leukemia virus with Cre-LoxP excisible coding sequences allowing superinfection, transgene delivery, and generation of host genomic deletionsImmortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neuronsHuman cytomegalovirus (HCMV) immediate-early enhancer/promoter specificity during embryogenesis defines target tissues of congenital HCMV infection.Novel bovine lentiviral vectors based on Jembrana disease virus.Genetic regulatory elements introduced into neural stem and progenitor cell populations.Novel Tat-encoding bicistronic human immunodeficiency virus type 1-based gene transfer vectors for high-level transgene expression.Gene silencing as a threat to the success of gene therapy.Gene transfer into rat brain using adenoviral vectors.The E6 and E7 genes of human papillomavirus type 6 have weak immortalizing activity in human epithelial cells.5-azacytidine induces transgene silencing by DNA methylation in Chinese hamster cells.Gene therapy for Parkinson's disease: review and update.Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes.Particle-mediated gene therapy of wounds.Growth factors secreted by fibroblasts: role in healing diabetic foot ulcers.Topical colchicine selection of keratinocytes transduced with the multidrug resistance gene (MDR1) can sustain and enhance transgene expression in vivo.Haemophilias: advances towards genetic engineering replacement therapy.In vivo assessment of gene delivery to keratinocytes by lentiviral vectorsIntraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transferSustained delivery of erythropoietin in mice by genetically modified skin fibroblastsGene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in mice.Retroviral vector sequences inhibit human beta-globin gene expression in transgenic mice.Development of transforming function during transduction of proto-ras into Harvey sarcoma virus.Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transduction.Current status and future prospects of gene therapy technologies toward the treatment of intractable skin diseases.Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo.Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells.Gene transfer in tissue repair: status, challenges and future directions.Long-term production and delivery of human growth hormone in vivoHighly efficient and sustained gene transfer in adult neurons with a lentivirus vector.Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo.Reactivation of silenced, virally transduced genes by inhibitors of histone deacetylase.Selective tropism of liver stem cells to hepatocellular carcinoma in vivo.Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells.Genetic modification of hematopoietic stem cells with nonviral systems: past progress and future prospects.Transplanted long-term cultured pre-BI cells expressing calpastatin are resistant to B cell receptor-induced apoptosis.NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection.
P2860
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P2860
Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Genetically modified skin fibr ...... y inactivate introduced genes.
@en
Genetically modified skin fibr ...... y inactivate introduced genes.
@nl
type
label
Genetically modified skin fibr ...... y inactivate introduced genes.
@en
Genetically modified skin fibr ...... y inactivate introduced genes.
@nl
prefLabel
Genetically modified skin fibr ...... y inactivate introduced genes.
@en
Genetically modified skin fibr ...... y inactivate introduced genes.
@nl
P2093
P2860
P356
P1476
Genetically modified skin fibr ...... y inactivate introduced genes.
@en
P2093
A D Miller
G J Rosman
T D Palmer
W R Osborne
P2860
P304
P356
10.1073/PNAS.88.4.1330
P407
P577
1991-02-01T00:00:00Z