In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development. - Wikidata - awgldk - TriplyDB

In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.

In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.

http://www.wikidata.org/entity/Q34602617

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Beyond generalized hair cells: molecular cues for hair cell types The genetics of hair cell development and regeneration Molecular mechanisms of inner ear development Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.The regulation of gene expression in hair cells Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion Characterization of the transcriptome of nascent hair cells and identification of direct targets of the Atoh1 transcription factor Evolution of vertebrate mechanosensory hair cells and inner ears: toward identifying stimuli that select mutation driven altered morphologies.Atoh1 as a Coordinator of Sensory Hair Cell Development and Regeneration in the Cochlea.In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1 The Role of Atonal Factors in Mechanosensory Cell Specification and Function Understanding the evolution and development of neurosensory transcription factors of the ear to enhance therapeutic translation.Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency.Mutational ataxia resulting from abnormal vestibular acquisition and processing is partially compensated for Large-scale quality analysis of published ChIP-seq data.Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity.A novel Atoh1 "self-terminating" mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability.Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival.Chimeras taking shape: potential functions of proteins encoded by chimeric RNA transcripts.A transcription factor network specifying inhibitory versus excitatory neurons in the dorsal spinal cord.Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells.A new mutation of the Atoh1 gene in mice with normal life span allows analysis of inner ear and cerebellar phenotype in aging.Opportunities and limits of the one gene approach: the ability of Atoh1 to differentiate and maintain hair cells depends on the molecular context In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord ATOH1 Can Regulate the Tumorigenicity of Gastric Cancer Cells by Inducing the Differentiation of Cancer Stem Cells.Regulation of POU4F3 gene expression in hair cells by 5' DNA in mice.Old and new functions of proneural factors revealed by the genome-wide characterization of their transcriptional targets.Neuronal specification exploits the inherent flexibility of cell-cycle gap phases.Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo TFE2 and GATA3 enhance induction of POU4F3 and myosin VIIa positive cells in nonsensory cochlear epithelium by ATOH1.A comprehensive view of nuclear receptor cancer cistromes Cerebellum Development and Tumorigenesis: A p53-Centric Perspective.Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti.MUC4 is negatively regulated through the Wnt/β-catenin pathway via the Notch effector Hath1 in colorectal cancer.Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells Transcriptional Regulation by ATOH1 and its Target SPDEF in the Intestine.The role of Atonal transcription factors in the development of mechanosensitive cells.

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In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development.

http://www.wikidata.org/entity/Q34602617

description

2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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type

label

In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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prefLabel

In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

@ast

In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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Proceedings of the National Academy of Sciences of the United States of America

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In vivo Atoh1 targetome reveal ...... ulates cerebellar development.

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Adriano Flora

http://www.w3.org/2001/XMLSchema#string

Liguo Wang

http://www.w3.org/2001/XMLSchema#string

Tiemo J Klisch

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Wei Li

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Yuanxin Xi

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P2860

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists

Merkel cells are essential for light-touch responses.

Cerebellar development transcriptome database (CDT-DB): Profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum

Atonal homolog 1 is a tumor suppressor gene

Math1 target genes are enriched with evolutionarily conserved clustered E-box binding sites

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway

A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons

Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers

Math1: an essential gene for the generation of inner ear hair cells

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3288-3293

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108

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21300888

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3044384

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