Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection
about
Molecular and cellular insights into T cell exhaustionInterleukin-10 determines viral clearance or persistence in vivoInnate and Adaptive Immune Regulation During Chronic Viral InfectionsAdvanced molecular surveillance of hepatitis C virusRegulatory function of cytomegalovirus-specific CD4+CD27-CD28- T cells.Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection.IL-10 directly suppresses CD4 but not CD8 T cell effector and memory responses following acute viral infection.IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infectionOpposing positive and negative regulation of T cell activity during viral persistence.Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustionDynamics of regulatory T-cells during pregnancy: effect of HIV infection and correlations with other immune parameters.T-cell exhaustion: characteristics, causes and conversion.Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels.Distinctive features of CD4+ T cell dysfunction in chronic viral infections.Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infectionThe transcription factor FoxO1 sustains expression of the inhibitory receptor PD-1 and survival of antiviral CD8(+) T cells during chronic infectionInduction and function of virus-specific CD4+ T cell responses.Viral persistence redirects CD4 T cell differentiation toward T follicular helper cellsProtective efficacy of individual CD8+ T cell specificities in chronic viral infectionT cell exhaustion during persistent viral infections.Update on hepatitis C virus-specific immunityIRF4 Regulates the Ratio of T-Bet to Eomesodermin in CD8+ T Cells Responding to Persistent LCMV Infection.Type I and Type II Interferon Coordinately Regulate Suppressive Dendritic Cell Fate and Function during Viral PersistenceEmergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infectionA Jekyll and Hyde Profile: Type 1 Interferon Signaling Plays a Prominent Role in the Initiation and Maintenance of a Persistent Virus Infection.Translating insights from persistent LCMV infection into anti-HIV immunity.The role of IL-10 in regulating immunity to persistent viral infectionsIL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infection.PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysisA Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control.Networking at the level of host immunity: immune cell interactions during persistent viral infectionsIL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection.Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.Demethylation of the PD-1 Promoter Is Imprinted during the Effector Phase of CD8 T Cell Exhaustion.Exploitation of Interleukin-10 (IL-10) Signaling Pathways: Alternate Roles of Viral and Cellular IL-10 in Rhesus Cytomegalovirus Infection.T cell exhaustion: from pathophysiological basics to tumor immunotherapy.Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.Extrinsic Protein Tyrosine Phosphatase Non-Receptor 22 Signals Contribute to CD8 T Cell Exhaustion and Promote Persistence of Chronic Lymphocytic Choriomeningitis Virus Infection.Nasopharyngeal carcinoma-associated Epstein-Barr virus-encoded oncogene latent membrane protein 1 potentiates regulatory T-cell function.Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults.
P2860
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P2860
Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Reprogramming of antiviral T c ...... ing persistent viral infection
@ast
Reprogramming of antiviral T c ...... ing persistent viral infection
@en
Reprogramming of antiviral T c ...... ing persistent viral infection
@nl
type
label
Reprogramming of antiviral T c ...... ing persistent viral infection
@ast
Reprogramming of antiviral T c ...... ing persistent viral infection
@en
Reprogramming of antiviral T c ...... ing persistent viral infection
@nl
prefLabel
Reprogramming of antiviral T c ...... ing persistent viral infection
@ast
Reprogramming of antiviral T c ...... ing persistent viral infection
@en
Reprogramming of antiviral T c ...... ing persistent viral infection
@nl
P2860
P356
P1476
Reprogramming of antiviral T c ...... ing persistent viral infection
@en
P2093
David G Brooks
Michael B A Oldstone
P2860
P304
P356
10.1172/JCI26856
P407
P577
2006-05-18T00:00:00Z