Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria - Wikidata - awgldk - TriplyDB

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

http://www.wikidata.org/entity/Q34621573

about

RNA mediated Toll-like receptor stimulation in health and disease Role of interleukin-10 in malaria: focusing on coinfection with lethal and nonlethal murine malaria parasites Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice Toxoplasma gondii upregulates interleukin-12 to prevent Plasmodium berghei-induced experimental cerebral malaria.Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria.An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malaria Loss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malaria Formal modeling and analysis of the MAL-associated biological regulatory network: insight into cerebral malaria.DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum.A novel carbon monoxide-releasing molecule fully protects mice from severe malaria In vivo antimalarial evaluation of some 2,3-disubstituted-4(3H)-quinazolinone derivatives.TLR9 and MyD88 are crucial for the development of protective immunity to malaria.Neutrophil paralysis in Plasmodium vivax malaria.DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.The host genetic diversity in malaria infection.Plasmodium-infected erythrocytes (pRBC) induce endothelial cell apoptosis via a heme-mediated signaling pathway Expression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study.A novel small-molecule enantiomeric analogue of traditional (-)-morphinans has specific TLR9 antagonist properties and reduces sterile inflammation-induced organ damage.Toll-like receptor 7 mediates early innate immune responses to malaria.Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection.Inflammation and adaptive immunity in Parkinson's disease.Microbial translocation in HIV infection: causes, consequences and treatment opportunities.New approaches in antimalarial drug discovery and development: a review.Innate immunity and neuroinflammation.Effect of malaria components on blood mononuclear cells involved in immune response.Parasite virulence, co-infections and cytokine balance in malaria.Do you see what I see: Recognition of protozoan parasites by Toll-like receptors.Toll-like receptor signaling in parasitic infections.A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria.Recent progress in the development of Toll-like receptor (TLR) antagonists.Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study.Blood-stage malaria of Plasmodium chabaudi induces differential Tlr expression in the liver of susceptible and vaccination-protected Balb/c mice.Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts.Infectious diseases: new leads for tackling malaria.Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice.The Emerging Role of Pattern Recognition Receptors in the Pathogenesis of Malaria.Plasmodium vivax infection impairs regulatory T cell suppressive function during acute malaria

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P2860

Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria

http://www.wikidata.org/entity/Q34621573

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2011 nî lūn-bûn

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2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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Proceedings of the National Academy of Sciences of the United States of America

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Therapeutical targeting of nuc ...... experimental cerebral malaria

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Douglas T Golenbock

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Fabian Gusovsky

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Hans Hansen

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Jeffrey Rose

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Marc Lamphier

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Rosane B de Oliveira

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Sally T Ishizaka

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Wanjun Zheng

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P2860

Human malarial disease: a consequence of inflammatory cytokine release

A world malaria map: Plasmodium falciparum endemicity in 2007

Artemisinin Resistance in Plasmodium falciparum Malaria

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: cell signaling receptors, glycosylphosphatidylinositol (GPI) structural requirement, and regulation of GPI activity

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

Murine cerebral malaria development is independent of toll-like receptor signaling

Hemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors.

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3689-3694

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9

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108

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Ricardo Tostes Gazzinelli

Bernardo S Franklin

Marco Antônio Ataíde

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2011-02-08T00:00:00Z

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49820077

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21303985

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cerebral malaria

Toll-like receptor

malaria prevention

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3048158

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