Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria
about
RNA mediated Toll-like receptor stimulation in health and diseaseRole of interleukin-10 in malaria: focusing on coinfection with lethal and nonlethal murine malaria parasitesInsufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout miceToxoplasma gondii upregulates interleukin-12 to prevent Plasmodium berghei-induced experimental cerebral malaria.Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria.An N-ethyl-N-nitrosourea (ENU)-induced dominant negative mutation in the JAK3 kinase protects against cerebral malariaLoss of Toll-like receptor 7 alters cytokine production and protects against experimental cerebral malariaFormal modeling and analysis of the MAL-associated biological regulatory network: insight into cerebral malaria.DNA Sensing via TLR-9 Constitutes a Major Innate Immunity Pathway Activated during Erythema Nodosum Leprosum.A novel carbon monoxide-releasing molecule fully protects mice from severe malariaIn vivo antimalarial evaluation of some 2,3-disubstituted-4(3H)-quinazolinone derivatives.TLR9 and MyD88 are crucial for the development of protective immunity to malaria.Neutrophil paralysis in Plasmodium vivax malaria.DNA-Containing Immunocomplexes Promote Inflammasome Assembly and Release of Pyrogenic Cytokines by CD14+ CD16+ CD64high CD32low Inflammatory Monocytes from Malaria Patients.The host genetic diversity in malaria infection.Plasmodium-infected erythrocytes (pRBC) induce endothelial cell apoptosis via a heme-mediated signaling pathwayExpression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study.A novel small-molecule enantiomeric analogue of traditional (-)-morphinans has specific TLR9 antagonist properties and reduces sterile inflammation-induced organ damage.Toll-like receptor 7 mediates early innate immune responses to malaria.Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.Toll-Like Receptor 2 Is Required for Inflammatory Process Development during Leishmania infantum Infection.Inflammation and adaptive immunity in Parkinson's disease.Microbial translocation in HIV infection: causes, consequences and treatment opportunities.New approaches in antimalarial drug discovery and development: a review.Innate immunity and neuroinflammation.Effect of malaria components on blood mononuclear cells involved in immune response.Parasite virulence, co-infections and cytokine balance in malaria.Do you see what I see: Recognition of protozoan parasites by Toll-like receptors.Toll-like receptor signaling in parasitic infections.A meta-analysis of TLR4 and TLR9 SNPs implicated in severe malaria.Recent progress in the development of Toll-like receptor (TLR) antagonists.Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study.Blood-stage malaria of Plasmodium chabaudi induces differential Tlr expression in the liver of susceptible and vaccination-protected Balb/c mice.Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts.Infectious diseases: new leads for tackling malaria.Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice.The Emerging Role of Pattern Recognition Receptors in the Pathogenesis of Malaria.Plasmodium vivax infection impairs regulatory T cell suppressive function during acute malaria
P2860
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P2860
Therapeutical targeting of nucleic acid-sensing Toll-like receptors prevents experimental cerebral malaria
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Therapeutical targeting of nuc ...... experimental cerebral malaria
@ast
Therapeutical targeting of nuc ...... experimental cerebral malaria
@en
Therapeutical targeting of nuc ...... experimental cerebral malaria
@nl
type
label
Therapeutical targeting of nuc ...... experimental cerebral malaria
@ast
Therapeutical targeting of nuc ...... experimental cerebral malaria
@en
Therapeutical targeting of nuc ...... experimental cerebral malaria
@nl
prefLabel
Therapeutical targeting of nuc ...... experimental cerebral malaria
@ast
Therapeutical targeting of nuc ...... experimental cerebral malaria
@en
Therapeutical targeting of nuc ...... experimental cerebral malaria
@nl
P2093
P2860
P50
P921
P356
P1476
Therapeutical targeting of nuc ...... experimental cerebral malaria
@en
P2093
Douglas T Golenbock
Fabian Gusovsky
Hans Hansen
Jeffrey Rose
Marc Lamphier
Rosane B de Oliveira
Sally T Ishizaka
Wanjun Zheng
P2860
P304
P356
10.1073/PNAS.1015406108
P407
P577
2011-02-08T00:00:00Z