Adeno-associated virus vectors serotype 2 induce prolonged proliferation of capsid-specific CD8+ T cells in mice.
about
Self-complementary AAVs induce more potent transgene product-specific immune responses compared to a single-stranded genomeCapsid-specific T-cell responses to natural infections with adeno-associated viruses in humans differ from those of nonhuman primatesTransient and intensive pharmacological immunosuppression fails to improve AAV-based liver gene transfer in non-human primates.The threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing.Gene Therapy for Duchenne muscular dystrophy.Efficacy and Safety of rAAV2-ND4 Treatment for Leber's Hereditary Optic NeuropathyEngineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.Kinetics of adeno-associated virus serotype 2 (AAV2) and AAV8 capsid antigen presentation in vivo are identical.Immune responses to AAV vectors: overcoming barriers to successful gene therapyCD8+ T cell recognition of epitopes within the capsid of adeno-associated virus 8-based gene transfer vectors depends on vectors' genome.Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors.Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.Unraveling the complex story of immune responses to AAV vectors trial after trial.Regulatory and Exhausted T Cell Responses to AAV Capsid.Synergistic inhibition of PARP-1 and NF-κB signaling downregulates immune response against recombinant AAV2 vectors during hepatic gene therapy.Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopesEmerging Issues in AAV-Mediated In Vivo Gene Therapy.
P2860
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P2860
Adeno-associated virus vectors serotype 2 induce prolonged proliferation of capsid-specific CD8+ T cells in mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@ast
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@en
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@nl
type
label
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@ast
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@en
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@nl
prefLabel
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@ast
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@en
Adeno-associated virus vectors ...... specific CD8+ T cells in mice.
@nl
P2093
P2860
P356
P1433
P1476
Adeno-associated virus vectors ...... -specific CD8+ T cells in mice
@en
P2093
Dongming Zhou
Hildegund C J Ertl
Steven Tuyishime
Te-Lang Wu
Weidong Xiao
Wynetta Giles-Davis
P2860
P304
P356
10.1038/MT.2010.267
P577
2010-12-14T00:00:00Z