Capsid-specific T-cell responses to natural infections with adeno-associated viruses in humans differ from those of nonhuman primates
about
Adeno-associated virus (AAV) vectors in gene therapy: immune challenges and strategies to circumvent them.Combinatorial anti-HIV gene therapy: using a multipronged approach to reach beyond HAARTB-Cell Depletion is Protective Against Anti-AAV Capsid Immune Response: A Human Subject Case StudyThe threefold protrusions of adeno-associated virus type 8 are involved in cell surface targeting as well as postattachment processing.Gene Therapy for Duchenne muscular dystrophy.An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8+ T CellsExtended normal life after AAVrh10-mediated gene therapy in the mouse model of Krabbe disease.Adeno-associated virus capsid antigen presentation is dependent on endosomal escape.Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.Effects of immunosuppression on circulating adeno-associated virus capsid-specific T cells in humansEnhanced T cell function in a mouse model of human glycosylation.IL12-mediated liver inflammation reduces the formation of AAV transcriptionally active forms but has no effect over preexisting AAV transgene expression.Immune responses to AAV vectors: overcoming barriers to successful gene therapyPreclinical toxicity evaluation of AAV for pain: evidence from human AAV studies and from the pharmacology of analgesic drugs.Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia.Unraveling the complex story of immune responses to AAV vectors trial after trial.In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model.Prevention and Reversal of Antibody Responses Against Factor IX in Gene Therapy for Hemophilia B.Humoral and cell-mediated immune response, and growth factor synthesis after direct intraarticular injection of rAAV2-IGF-I and rAAV5-IGF-I in the equine middle carpal joint.Can Viruses be Modified to Achieve Sustained Gene Transfer.Covert warfare against the immune system: decoy capsids, stealth genomes, and suppressors.AAV vector biology in primates: finding the missing link?Gene Therapy for Hemophilia: Progress to Date.Recent progress and considerations for AAV gene therapies targeting the central nervous system.
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P2860
Capsid-specific T-cell responses to natural infections with adeno-associated viruses in humans differ from those of nonhuman primates
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Capsid-specific T-cell respons ...... rom those of nonhuman primates
@ast
Capsid-specific T-cell respons ...... rom those of nonhuman primates
@en
type
label
Capsid-specific T-cell respons ...... rom those of nonhuman primates
@ast
Capsid-specific T-cell respons ...... rom those of nonhuman primates
@en
prefLabel
Capsid-specific T-cell respons ...... rom those of nonhuman primates
@ast
Capsid-specific T-cell respons ...... rom those of nonhuman primates
@en
P2093
P2860
P356
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Capsid-specific T-cell respons ...... rom those of nonhuman primates
@en
P2093
Hildegund C J Ertl
Larissa H Haut
Marcio O Lasaro
Shih Wen Lin
P2860
P304
P356
10.1038/MT.2011.81
P577
2011-05-17T00:00:00Z